cell Archives - Page 2 of 5 - Family Medicine News

Novel regulator of mitochondrial cell death reveals a promising target for cancer therapy

20.09.2019 Health Problems

Researchers at The Wistar Institute have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. They also found that expression of MFF is regulated by Myc, a ubiquitous mediator of cell proliferation that contributes to development of many cancer types. These results were published online in […]

100-year-old scientific mystery solved: Researchers discover role of nuclear glycogen in non-small cell lung cancers

13.09.2019 Health Problems

Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers. Published in Cell Metabolism, the research centers on the function of glycogen accumulation in the nucleus of a cell. Glycogen is known […]

Targeting cell division in pancreatic cancer

19.08.2019 Health Problems

Pancreatic cancer is one of the deadliest cancers, with patients surviving on average less than a year once the disease has spread. There is an urgent need to evaluate more therapeutic targets. The chemotherapeutic agent abemaciclib is effective in treating breast cancer, but there is limited preclinical evaluation of this targeted therapy in treating pancreatic cancer. New research from Sidney […]

Injectable ‘bone spackling’: A cell therapy approach to heal complex fractures

01.08.2019 Health Problems

Large, complex bone wounds are hard for doctors and patients alike to contend with. They often require grafts and multiple surgeries. Jan Stegemann, a University of Michigan professor of biomedical engineering, is reprogramming adult cells from bone marrow so that they can be injected directly into a wound and grow into bone. The marrow-derived cells are known as progenitor cells, […]

Mechanical forces control cell fate during brain formation

29.07.2019 Health Problems

A new study coordinated by the Research Group in Developmental Biology at UPF shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during morphogenesis to regulate the balance between progenitor stem cells and differentiated neurons. The study has been published in the journal Development. In vertebrates, the central […]

Researchers discover new cause of cell aging

26.07.2019 Health Problems

New research from the USC Viterbi School of Engineering could be key to our understanding of how the aging process works. The findings potentially pave the way for better cancer treatments and revolutionary new drugs that could vastly improve human health in the twilight years. The work, from Assistant Professor of Chemical Engineering and Materials Science Nick Graham and his […]

Team breaks down major players in cell to score future cancer therapy wins

11.07.2019 Health Problems

A soccer team is made up of 11 players with each person having a specific role and place on the field. In the world of biology, each individual cell also has many moving parts and pieces, each with specific roles and places to be. If one of those pieces isn’t working correctly, it can affect the entire cell, much like […]

Microfluidics device captures circulating cancer cell clusters

19.06.2019 Health Problems

Cancer touches nearly everyone in one way or another, and regrettably, it will claim another 600,000 lives in the U.S. in 2019, according to the American Cancer Society. Researchers from San Diego State University, TumorGen MDx Inc., and Sanford Burnham Prebys Medical Discovery Institute set out to explore a seemingly basic question: What is it about cancer that kills? The […]

Fat cell discovery could help combat obesity-related health issues

30.04.2019 Health Problems

Researchers have discovered differences in fat cells that could potentially identify people predisposed to metabolic diseases such as diabetes and fatty liver disease. The world-first discovery also identified ‘fast burning’ fat cells that if unlocked might help people lose weight. About 70 per cent of Australians are overweight or obese, which has been linked to metabolic disease risk. The University […]

Biologists find a way to boost intestinal stem cell populations

29.03.2019 Health Problems

Cells that line the intestinal tract are replaced every few days, a high rate of turnover that relies on a healthy population of intestinal stem cells. MIT and University of Tokyo biologists have now found that aging takes a toll on intestinal stem cells and may contribute to increased susceptibility to disorders of the gastrointestinal tract. The researchers also showed […]

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