How to fight side effects of hormone therapy for prostate cancer

Men on hormone therapy for prostate cancer may benefit significantly from hitting the gym with fellow patients and choosing more veggies and fewer cheeseburgers, a new study suggests. Androgen deprivation therapy is a powerful tool against prostate cancer, and more and more men are opting for the treatment as a growing array of hormone-based therapies become available. But it comes […]

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Flare-responsive hydrogel developed to treat arthritis

Arthritis flares – the unpredictable and often sudden worsening of arthritis symptoms—can be debilitating. These episodes can make the management of inflammatory arthritis, which includes rheumatoid arthritis and psoriatic arthritis, challenging for patients and physicians. But investigators at Brigham and Women’s Hospital have found that flares may also represent an important opportunity for improving treatment options for patients. In experiments […]

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Mathematical modeling offers new way to understand variable responses to targeted therapy

Cancer therapies that target a specific protein have improved outcomes for patients. However, many patients eventually develop resistance to these targeted therapies and their cancer comes back. It is believed that differences among tumor cells, or heterogeneity, may contribute to this drug resistance. Moffitt Cancer Center researchers are using a unique approach by combining typical cell culture studies with mathematical […]

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Sulfur amino acid restriction could amount to new dietary approach to health

The longevity and health improvements seen in animals on sulfur amino acid-restricted diets could translate to people, according to Penn State College of Medicine researchers who recently conducted a review of published studies. More research is needed to confirm the benefits in people, the scientists said. Amino acids are the building blocks of all proteins in the body. A subcategory […]

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ACA has provided better access to care for cancer survivors

(HealthDay)—Cancer survivors are more likely to have difficulty accessing and affording health care, but the proportion reporting these issues is decreasing, according to a study published online March 29 in JAMA Oncology. Ryan D. Nipp, M.D., M.P.H., from Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues used data from the National Health Interview Survey to examine health […]

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Researchers find alternate path for Listeria to sicken people

Purdue University scientists have found another pathway that Listeria uses to enter the bloodstream, suggesting that forms of the foodborne bacteria considered benign may be more dangerous than once thought. About 600 million people around the world contract listeriosis each year, with 420,000 dying, according to the World Health Organization. In the U.S., 1,600 people are infected each year, causing […]

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Relapse in major depression linked to brain cortical changes

(HealthDay)—For patients with major depressive disorder (MDD), relapse is associated with brain cortical changes over two years, according to a study published online March 28 in JAMA Psychiatry. Dario Zaremba, from the University of Münster in Germany, and colleagues conducted a longitudinal case-control study involving patients with acute MDD at baseline and healthy controls. Participants were subdivided into groups with […]

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Preventing tumors from shedding their identifying proteins allows immune system to attack

A team of researchers with the Dana-Farber Cancer Institute and Brigham and Women’s Hospital in the U.S. has found that introducing an antibody into a cancerous mouse model prevented the escape of ligands from a tumor surface allowing natural killer cells to attack. In their paper published in the journal Science, the group describes their technique and how well it […]

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