New biological research framework for Alzheimer’s seeks to spur discovery

The research community now has a new framework toward developing a biologically-based definition of Alzheimer’s disease. This proposed “biological construct” is based on measurable changes in the brain and is expected to facilitate better understanding of the disease process and the sequence of events that lead to cognitive impairment and dementia. With this construct, researchers can study Alzheimer’s, from its […]

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Study finds how fat tissue shunts energy to tumors

Obesity is the second-leading preventable cause of cancer and represents one of the greatest threats to global human health. But it has not been clear exactly how whole-body metabolism affects tumor formation. In particular, the molecular mechanisms by which fat cells communicate with tumor tissue remain poorly understood. Sanford Prebys Medical Discovery Institute (SBP) researchers recently addressed this question, revealing […]

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Study confirms that inflammation during pregnancy is linked to baby’s brain

Inflammation is a normal part of the body’s response to infection, chronic stress or obesity. In pregnant women, it is believed that heightened inflammation increases the risk of mental illness or brain development problems in children. A study conducted by researchers at OHSU in Portland, Oregon, has established a link between inflammation in pregnant women and the way the newborn […]

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Payments to doctors linked to prescription practices for two cancer types

Physicians who received payment from pharmaceutical companies for meals, talks and travel were more likely to prescribe those companies’ drugs for two cancer types, a University of North Carolina Lineberger Comprehensive Cancer Center-led study has found. The study was published Monday in the Journal of the American Medical Association Internal Medicine. The preliminary findings were presented last year at the […]

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Machine learning finds tumor gene variants and sensitivity to drugs in The Cancer Genome Atlas

Matching unique genetic information from cancer patients’ tumors with treatment options – an emerging area of precision medicine efforts – often fails to identify all patients who may respond to certain therapies. Other molecular information from patients may reveal these so-called “hidden responders,” according to a Penn Medicine study in Cell Reports this week. The findings are published alongside several […]

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Reading to your kids might boost their social skills

(HealthDay)—Parents who read to their infants and toddlers may help them develop skills that pay big dividends when they start school, a new study suggests. Specifically, reading aloud and pretend play may offset disruptive behaviors—such as hyperactivity and aggression—and improve attention, researchers found. “When you read with your child, it’s really a warm, nice time together,” said lead researcher Dr. […]

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Payments to doctors linked to prescription practices for two cancer types

Physicians who received payment from pharmaceutical companies for meals, talks and travel were more likely to prescribe those companies’ drugs for two cancer types, a University of North Carolina Lineberger Comprehensive Cancer Center-led study has found. The study was published Monday in the Journal of the American Medical Association Internal Medicine. The preliminary findings were presented last year at the […]

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Caregiving costs for heart disease and stroke survivors projected to soar to $128 billion by 2035

In a new analysis released today, the American Heart Association projects that the cost of informal caregiving for Americans with heart disease and stroke will more than double from $61 billion in 2015 to $128 billion by 2035. These new data on caregiving would increase the association’s predicted 2035 price tag for cardiovascular disease (CVD) total costs to $1.2 trillion […]

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