therapy Archives - Family Medicine News

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

04.12.2019 Health Problems

Kidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression with an experimental drug called tivozanib compared to an alternative approved by the U.S. Food and Drug Administration, according to a City of Hope-led study. “This agent has shown in clinical trials to be effective in delaying cancer growth beyond established […]

Genetic diversity facilitates cancer therapy

08.11.2019 Health Problems

The constant battle against infectious pathogens has had a decisive influence on the human immune system over the course of our evolution. A key role in our adaptation to pathogens is played by HLA molecules. These proteins activate the immune system by presenting it with fragments of pathogens that have entered the body. People with a wide variety of different […]

To monitor cancer therapy, researchers tag CAR T cells with imaging markers

05.11.2019 Health Problems

With CAR T cell therapy, a patient’s own immune cells are genetically modified and inserted back into the body to find and kill cancer. This form of immunotherapy has already revolutionized some cancer treatments, but once the CAR T cells are inside a patient, where do they go? How do doctors know that they have successfully reached their target and […]

New gene therapy for epilepsy provides on-demand release of endogenous substance

30.10.2019 Health Problems

Universitätsmedizin Berlin and the Medical University of Innsbruck have developed a new therapeutic concept for the treatment of temporal lobe epilepsy. It represents a gene therapy capable of suppressing seizures at their site of origin on demand. Having been shown to be effective in an animal model, the new method will now be optimized for clinical use. Results from this […]

Novel regulator of mitochondrial cell death reveals a promising target for cancer therapy

20.09.2019 Health Problems

Researchers at The Wistar Institute have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. They also found that expression of MFF is regulated by Myc, a ubiquitous mediator of cell proliferation that contributes to development of many cancer types. These results were published online in […]

Algorithm based on response, biology guides neuroblastoma therapy

05.09.2019 Health Problems

(HealthDay)—Use of a response- and biology-based treatment algorithm for intermediate-risk neuroblastoma is associated with excellent survival and reduces treatment for some patients, according to a study published online Aug. 6 in the Journal of Clinical Oncology. Clare J. Twist, M.D., from the Roswell Park Cancer Institute in Buffalo, New York, and colleagues enrolled 404 evaluable patients between 2007 and 2011 […]

MDM2 counteracts resistance to CDK4/6 inhibitors for melanoma therapy

16.08.2019 Health Problems

A study from Vanderbilt-Ingram Cancer Center and the Department of Veterans Affairs led by Anna Vilgelm, MD, Ph.D., and Ann Richmond, Ph.D., has identified a possible second-line treatment for melanoma patients. The potential treatment would render CDK4/6 inhibitors, a class of drugs prescribed for some breast cancers, also effective against melanoma by combining the inhibitors with MDM2 compounds, which are […]

Injectable ‘bone spackling’: A cell therapy approach to heal complex fractures

01.08.2019 Health Problems

Large, complex bone wounds are hard for doctors and patients alike to contend with. They often require grafts and multiple surgeries. Jan Stegemann, a University of Michigan professor of biomedical engineering, is reprogramming adult cells from bone marrow so that they can be injected directly into a wound and grow into bone. The marrow-derived cells are known as progenitor cells, […]

Smart brain stimulators: Next-gen parkinson’s disease therapy

29.07.2019 Health Problems

Researchers at the University of Houston have found neuro biomarkers for Parkinson’s disease that can help create the next generation of “smart” deep brain stimulators, able to respond to specific needs of Parkinson’s disease patients. Those with the disease often undergo the high-frequency brain stimulation, a well-established therapy for the progressive nervous system disorder that affects movement, but the therapy […]

Meghan King Edmonds and Son Try Oxygen Therapy After Brain Damage Diagnosis

18.07.2019 Kids Health

In it together! Meghan King Edmonds tried oxygen therapy with her 13-month-old son, Hart, after his brain damage diagnosis. “Hart and I are taking our first dive in a hyperbaric oxygen chamber,” the Real Housewives of Orange County alum, 34, captioned her Wednesday, July 17, Instagram Story. “The goal is with repeated and regular ‘dives’ his brain cells get so […]

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