Machine learning finds tumor gene variants and sensitivity to drugs in The Cancer Genome Atlas

Matching unique genetic information from cancer patients’ tumors with treatment options – an emerging area of precision medicine efforts – often fails to identify all patients who may respond to certain therapies. Other molecular information from patients may reveal these so-called “hidden responders,” according to a Penn Medicine study in Cell Reports this week. The findings are published alongside several […]

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Using mathematical models to determine the best chemotherapy schedules

Can mathematical models predict how can cancer cells respond to varied chemotherapy schedules? In other words, should cancers associated with fast-growing tumors, like brain cancer, be treated using a low drug dose administered continuously, as opposed to a high drug dose given periodically? Professor Paul Newton and Ph.D. recipient Jeffrey West have developed a tool that can predict the best […]

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Red or blue in the face? Study says conservatives show less emotion

If playing in a high-stakes poker game, it may be better to face opponents on the liberal side of the political spectrum. That’s because new research from the University of Nebraska–Lincoln has demonstrated a correlation between political ideology and facial expressivity: Conservatives have better poker faces, while liberals may allow more tells. Previous research has shown that people can identify […]

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