A system of check and balances in the blood

Hematopoietic stem cells (HSCs) give rise to blood and immune cells, and are therefore essential for survival. The group of Manuela Baccarini at the Max F. Perutz Laboratories, a joint venture of the University of Vienna and the Medical University of Vienna, has now shown how intracellular signaling can safeguard this delicate balance between activation and dormancy. Their results are […]

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Long-term psychological study confirms time is the best medicine against homesickness

Time heals homesickness – and quickly, according to a unique long-term study on international students. A propensity towards neuroticism and the desire to keep others happy are among the factors associated with the development of homesickness. However, the study also found that the level of homesickness among those currently studying abroad is generally low. The investigation was facilitated by a […]

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Resetting the epigenetic balance for cancer therapy

Though mutations in a gene called MLL3 are common across many types of cancers, their relationship to the development of the disease has been unclear. Now, a Northwestern Medicine study has identified an epigenetic imbalance that silences the expression of tumor-suppressing proteins, allowing cancerous cells to proliferate. In the study published in Nature Medicine, Northwestern investigators applied a simple molecular […]

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Many Americans say infectious and emerging diseases in other countries will threaten the US

An overwhelming majority of Americans (95%) think infectious and emerging diseases facing other countries will pose a ‘major’ or ‘minor’ threat to the U.S. in the next few years, but more than half (61%) say they are confident the federal government can prevent a major infectious disease outbreak in the U.S., according to a new national public opinion survey commissioned […]

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The Healthiest Soup Choices at Panera Bread

If you’re wary of preservatives and artificial ingredients, you can now order any of Panera’s soups with confidence—in January, the fast-casual chain officially removed all artificial colors, flavors, sweeteners, and preservatives from its soups, part of a larger plan announced to “clean up” the entire menu by the end of 2016. While we couldn’t be more pleased about this news, […]

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Mass-drug administration curbs scabies for asylum seekers in the Netherlands

In a new article published in PLOS Neglected Tropical Diseases, Sofanne J. Ravensbergen of the University of Groningen, and colleagues, found that a scabies intervention program (SIP) was effective in reducing the severity of scabies when introduced to the newly arrived Eritrean and Ethiopian asylum seekers who volunteered to take part in the program. Scabies, a skin infestation caused by […]

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Four questions—chronic pain and how it affects the brain

Chronic pain affects an estimated 100 million Americans, and its impact goes beyond physical discomfort. New research, led by University of Arizona psychologist Stephen Cowen, illustrates how chronic pain may impact cognitive abilities, such as decision making, as well. Cowen and UA professor of pharmacology Frank Porreca, along with their collaborators at Eli Lilly, investigated how pain impacts cognitive flexibility, […]

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