Researchers describe role of novel mutations in fosfomycin resistance

Researchers identified novel chromosomal mutations and described their role in the development of resistance of Escherichia coli (E. coli) to broad-spectrum antibiotic fosfomycin, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Researchers from France studied the genetic basis of fosfomycin resistance in a panel of E. coli isolates and found that certain […]

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Novel antioxidant makes old blood vessels seem young again

Older adults who take a novel antioxidant that specifically targets cellular powerhouses, or mitochondria, see age-related vascular changes reverse by the equivalent of 15 to 20 years within six weeks, according to new University of Colorado Boulder research. The study, published this week in the American Heart Association journal Hypertension, adds to a growing body of evidence suggesting pharmaceutical-grade nutritional […]

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Novel drug shows promise against acute myeloid leukemia

In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide (small protein) drug shows promise against the often-lethal cancer acute myeloid leukemia (AML) and describe how the drug works at the molecular level. The findings have led to a Phase I/II clinical trial for patients with advanced AML and […]

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Scientists develop novel cancer cell culture test kit for personalised, precise cancer therapy

A team of scientists led by Professor Lim Chwee Teck, Principal Investigator at the Mechanobiology Institute, Singapore (MBI) and the Department of Biomedical Engineering at the National University of Singapore (NUS) and NUS Ph.D. graduate Dr. Khoo Bee Luan, has developed a novel and robust cancer cell-based assay that could help clinicians to diagnose cancer, monitor the disease state and […]

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