novel Archives - Page 2 of 3 - Family Medicine News

Newly characterized molecule offers possibilities for novel Alzheimer’s treatments

04.08.2018 Health Problems

Alzheimer’s disease is an increasingly prevalent, neurodegenerative condition that erodes memory and other cognitive functions. Treatments for this complex disease have been elusive, although researchers have previously uncovered its main biological features: amyloid-beta plaques and tau tangles. A study by researchers from Brigham and Women’s Hospital (BWH), recently published in Acta Neuropathologica, investigated lesser-known molecules involved in tauopathies like Alzheimer’s. […]

Scientists develop novel drug that could potentially treat liver cancer more effectively

03.08.2018 Health Problems

A research team led by scientists from the Cancer Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has developed a novel peptide drug called FFW that could potentially stop the development of hepatocellular carcinoma (HCC), or primary liver cancer. This landmark discovery opens the door for more effective treatment of liver cancer with less side effects. […]

Novel PET imaging method could track and guide therapy for type 1 diabetes

03.08.2018 Health Problems

Researchers have discovered a new nuclear medicine test that could improve care of patients with type 1 diabetes. The new positron emission tomography (PET) imaging method could measure beta-cell mass, which would greatly enhance the ability to monitor and guide diabetes therapies. This study is reported in the featured article of the month in The Journal of Nuclear Medicine‘s August […]

Enzyme identified as possible novel drug target for sickle cell disease, Thalassemia

22.07.2018 Health Problems

Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease (SCD). Experiments in cultured human cells reveal that blocking the protein reduces the characteristic sickling that distorts the shape of red blood cells and gives the disease its name. “We […]

Novel therapy delays muscle atrophy in Lou Gehrig’s disease model

12.07.2018 Health Problems

Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig’s disease, according to a new study out of Case Western Reserve University School of Medicine. Researchers found high levels of the protein—called mitofusion 2 or Mfn2—prevented nerve degeneration, muscle atrophy, and paralysis in a mouse model of the disease. Since Mfn2 is often depleted […]

Researchers report novel method to quickly make therapeutic proteins from human blood

23.06.2018 Health Problems

UMBC researchers report novel method to quickly make therapeutic proteins from human blood Personalized medicine has incredible potential, but current approaches are still too expensive and time-consuming to have a big impact. A new paper in Scientific Reports looks at how to extract cellular protein synthesis machinery from human blood, and, by adding recombinant DNA to the extract, to produce […]

Study finds a novel and more practical way to measure kidney function

22.06.2018 Health Problems

Researchers working on a study to improve kidney function measurements have found a way to provide more accurate readings. Using an injectable biomarker, physicians were able to read the actual working capacity of the kidney in a clinical setting in half the time it used to take. Currently, physicians rely on estimated kidney function (or estimated glomerular filtration rate) to […]

Abdominal fat secretes novel adipokine promoting insulin resistance and inflammation

24.05.2018 Health Problems

An international research team in which the DZD is participating has identified a novel adipokine that favors the development of insulin resistance and systemic inflammation. In cases of severe obesity, this adipokine is secreted by the adipocytes of the abdominal fat tissue and released into the bloodstream. The new findings could contribute to the development of alternative approaches for the […]

Novel signal ID’d for microalbuminuria in europeans with T2DM

04.05.2018 Health Problems

(HealthDay)—A novel signal has been identified that is associated with microalbuminuria in Europeans with type 2 diabetes (T2D), according to a study published online April 27 in Diabetes. Natalie R. van Zuydam, Ph.D., from the University of Oxford in the United Kingdom, and colleagues conducted a genome-wide association study (GWAS) of diabetic kidney disease (DKD) in T2D using eight complementary […]

Novel pathway identified in development of acute myeloid leukemia with poor prognosis

25.04.2018 Health Problems

Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow that comprises 1 percent of all new cancer cases and almost 2 percent of cancer deaths in the U.S. The five-year survival rate for the disease is less than 20 percent. Researchers at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore […]

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