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Scientists at Scripps Research have uncovered a new strategy to kill tumors, including some triple-negative breast cancers, without harming healthy cells, a discovery that could lead to more ways to treat tumors while reducing side effects. The study, published recently in Nature Communications, shows that a molecule in cells, called Rad52, repairs special kinds of damaged DNA that accumulate in […]
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Cardiovascular disease (CVD) is the leading cause of morbidity and mortality and also contributes to huge health care expenditures in China. Therefore, accurate and early identification of high-risk individuals is important for CVD prevention. The China-PAR (Prediction for atherosclerotic CVD (ASCVD) Risk in China) project generated equations with excellent capacity to predict lifetime risk for ASCVD by incorporating four large […]
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New research: High burden of hepatitis C among people who inject drugs highlights the urgent need for harm reduction and treatment strategies Globally, more than one in three (39%) people who have injected drugs in the last year are living with hepatitis C infection, according to new research from the National Drug and Alcohol Research Centre and the Kirby Institute […]
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International guidelines have been published for the first time to help doctors around the globe diagnose and manage patients with a very rare set of endocrine diseases known as pseudohypoparathyroidism and its related disorders, including Albright hereditary osteodystrophy (AHO). It’s the realization of a long-term goal for physician-scientist Dr. Emily Germain-Lee of the UConn School of Medicine and Connecticut Children’s […]
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Is it possible for microscopes to learn a bit about the brain? Even be taught by neuroscientists to reliably recognize parts of brain cells… all on their own? Though it may seem like something straight out of “The Jetsons”, a neuroscientist and software engineer in the lab of MPFI’s Scientific Director, Dr. Ryohei Yasuda, Ph.D., is developing new software with […]
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If you search the hashtag #BoPo — short for body positivity — on Instagram, you’ll find nearly 670,000 posts by individuals of all shapes and sizes celebrating their bodies. It’s just one sign of the rise of the body-positivity movement, propelled in recent years by celebrities such as Ashley Graham, who’s unafraid to flaunt her cellulite, and social media influencers like Jessamyn Stanley, who […]
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University of Queensland researchers have discovered how to reverse drug resistance in skin and mouth squamous cell carcinomas. UQ Diamantina Institute Associate Professor Nicholas Saunders said squamous cell carcinomas was curable when diagnosed early but difficult to eradicate once the cancer spread. “This cancer of the skin and mouth kills approximately 1,400 Australians each year,” Dr. Saunders said. “The drugs […]
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A tumor’s goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate. Without oxygen, these ever-dividing cells struggle to make enough aspartate, a crucial ingredient in many cellular processes. That’s the scenario worked out by […]
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Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops into atherosclerosis—deposits of cholesterol, fats and other substances that create plaque, clog arteries and promote heart attacks and stroke. The findings could lead to improved therapies for atherosclerosis, a leading cause of death worldwide. “We have known for decades that atherosclerosis is a disease of […]
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An international trial has found that a medicine commonly used to treat poisoning is effective in reducing deafness in children receiving chemotherapy for cancer. University of Melbourne and Royal Children’s Hospital paediatric oncologist Professor Michael Sullivan was international vice chair of the study, results of which are published in today’s New England Journal of Medicine. Professor Sullivan said the trial […]
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