Electrically stimulating the brain may restore movement after stroke

UC San Francisco scientists have improved mobility in rats that had experienced debilitating strokes by using electrical stimulation to restore a distinctive pattern of brain cell activity associated with efficient movement. The researchers say they plan to use the new findings to help develop brain implants that might one day restore motor function in human stroke patients. After a stroke, […]

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Gene editing technology may improve accuracy of predicting individuals’ heart disease risk

Scientists may now be able to predict whether carrying a specific genetic variant increases a person’s risk for disease using gene editing and stem cell technologies, according to new research in the American Heart Association’s journal Circulation. For the first time, the study demonstrates the unique potential of combining stem cell-based disease modeling (Induced pluripotent stem cells) and CRISPR/Cas9-mediated genome […]

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Early, intensive treatment of RA offers long-term benefits, may normalise mortality rates

The results of a 23-year, follow-up study presented today at the Annual European Congress of Rheumatology (EULAR 2018) suggest early, intensive treatment of rheumatoid arthritis has long-term benefits including the normalisation of mortality to levels consistent with the general population. “We know that the adverse effects of rheumatoid arthritis on the body only become truly apparent after more than a […]

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Tobacco aside, e-cigarette flavorings may harm blood vessels

Flavor additives used in electronic cigarettes and related tobacco products could impair blood vessel function and may be an early indicator of heart damage, according to new laboratory research in Arteriosclerosis, Thrombosis and Vascular Biology, an American Heart Association journal. The health effects of “combustible” tobacco products including traditional cigarettes and hookah are well-established, but the potential dangers of e-cigarettes […]

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Exercise may lower mortality in adult survivors of childhood CA

(HealthDay)—For adult survivors of childhood cancer, vigorous exercise in early adulthood is associated with reduced risk of mortality, according to a study published online June 3 in JAMA Oncology. Jessica M. Scott, Ph.D., from the Memorial Sloan Kettering Cancer Center in New York City, and colleagues conducted a multicenter cohort analysis among 15,450 adult cancer survivors diagnosed before age 21 […]

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Cattle may spread leptospirosis in Africa, study suggests

The bacterial infection leptospirosis is increasingly recognized as an important cause of fever in Africa. Now, researchers reporting in PLOS Neglected Tropical Diseases have analyzed the major risk factors for contracting leptospirosis and discovered that rice and cattle farming are associated with acute infection. Leptospirosis, caused by bacteria of the genus Leptospira, causes a wide range of symptoms and can […]

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Killing bacteria by silencing genes may be alternative to antibiotics

A new approach to killing C. difficile that silences key bacterial genes while sparing other bacteria may provide a new way to treat the most common hospital-acquired bacterial infection in the United States, according to researchers. While conventional antibiotics treat bacterial infections, they can also cause a condition in the colon called C. difficile infection, due to the drug killing […]

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Chemoradiotherapy before surgery may extend lives of pancreatic cancer patients

Pancreatic cancer patients treated with chemotherapy and radiotherapy before surgery may live longer than those who have immediate surgery, according to unpublished clinical trial results. The research, funded by the Dutch Cancer Society, looked at patients who had pancreatic cancer that could be removed by surgery because their cancer had not spread from the pancreas. Patients who had chemoradiotherapy before […]

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