Painkillers in pregnancy may affect baby’s future fertility

Taking painkillers during pregnancy could affect the fertility of the unborn child in later life, research suggests. The study identifies that these drugs may also affect the fertility of future generations, by leaving marks on DNA. The findings add to a growing body of evidence that certain medicines, including paracetamol, should be used with caution during pregnancy. Researchers stress that […]

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Self-inflicted gunshot wound survivors may deny suicide attempt, face barriers to care

Researchers have found that more than one-third of patients who denied that their self-inflicted gunshot wound resulted from a suicide attempt most likely had indeed tried to kill themselves, and commonly were sent home from the hospital without further mental health treatment. The findings indicate there are significant barriers to treatment for people who have made suicide attempts, and highlight […]

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Study may show how chronic early-life stress raises PTSD vulnerability

A collaboration between investigators at Massachusetts General Hospital and Khyber Medical University in Pakistan may have discovered how chronic stress experienced early in life increases vulnerability to post-traumatic stress disorder (PTSD) later in life. In their report published in Translational Psychiatry the researchers describe finding that chronic stress induces a persistent increase in the hormone ghrelin, both in a rat […]

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New rapid-fire method using pathology images, tumor data may help guide cancer therapies

By combining data on pathology images of 13 types of cancer and correlating that with clinical and genomic data, a Stony Brook University-led team of researchers are able to identify tumor-infiltrating lymphocytes (TILs), called TIL maps, which will enable cancer specialists to generate tumor-immune information from routinely gathered pathology slides. Published in Cell Reports , the paper details how TIL […]

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Early intervention may minimise later lung problems

A major study has found that controlling asthma through appropriate monitoring and medication is among several variables that can affect whether someone develops chronic obstructive pulmonary disease (COPD) in later life. The University of Melbourne-led study, published in The Lancet Respiratory Medicine, was the world’s first to characterise lung function trajectories that could lead to COPD in a large general […]

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Primary care doctors may be unsure when kids’ bad moods are serious or not

All children have moments of moodiness, but family medicine doctors and pediatricians may doubt their abilities to tell the difference between normal irritability and possibly bigger issues, according to Penn State researchers. When the researchers interviewed a group of health care providers, they found that the primary care providers and pediatricians were less confident than the child and adolescent psychiatrists […]

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Relaxation response may reduce blood pressure by altering expression of a set of genes

High blood pressure—or hypertension—is a major risk factor for heart attack and stroke that affects as many as 100 million Americans and 1 billion people worldwide. Decades of research have demonstrated that the relaxation response—the physiological and psychological opposite of the well-known fight-or-flight stress response that can be achieved through relaxation techniques like yoga or mediation – can reduce blood […]

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Gene-based tests may improve treatment for people with bipolar disorder

Bipolar affective disorder (BPAD) affects around 2% of the world’s population, leaving them with bouts of severe depression and episodes of what is commonly referred to as “mania”. A range of drug treatments are available, but choosing the right medication, or range of medications, can be a struggle – sometimes spanning many years. But new research aims to shorten this […]

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