Study provides insights into how fibrosis progresses in the human lung

A Yale-led collaborative study boosts scientific understanding of how the lung disease idiopathic pulmonary fibrosis (IPF) progresses, providing a roadmap for researchers to discover new treatment targets for the disease. The study, led by Naftali Kaminski, M.D., the Boehringer-Ingelheim Endowed Professor of Internal Medicine and chief of the Section of Pulmonary, Critical Care, and Sleep Medicine at Yale School of […]

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Scientists reveal novel oncogenic driver gene in human gastrointestinal stromal tumors

Sarcomas—cancers that arise from transformed mesenchymal cells (a type of connective tissue)—are quite deadly. Gastrointestinal stromal tumors (GISTs) are the most common human sarcoma and are initiated by activating mutations in the KIT receptor tyrosine kinase. Micro-GISTs are a smaller variation of clinical GISTs and are found in one-third of the general population without clinical symptoms. Although the micro-GISTs and […]

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Could prosthetic limbs one day be controlled by human thought?

For almost two decades, Stanford electrical engineering professor Krishna Shenoy and neuroscientists in his Neural Prosthetics Translational Laboratory have been working on implantable brain sensors that allow them to record and decipher the electrical activity of neurons that control body movement. The long-term goal: to build prosthetics that amputees and those with paralysis can control with their thoughts. Currently, the […]

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Lines blurring between human herpes simplex viruses

The line between the human herpes simplex viruses—HSV-1 and HSV-2—is blurrier than previously thought, according to a new study published this week in the Journal of Infectious Diseases. Researchers found that HSV-1 and HSV-2 are mixing together to result in several new, different recombinant versions of herpes. “The main implication is that HSV-1 and HSV-2 are continuing to recombine,” said […]

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New light-based technology reveals how cells communicate in human disease

Scientists at the University of York have developed a new technique that uses light to understand how cells communicate in human disease. All cells in the human body communicate with each other by releasing signalling molecules; this helps to ensure that tissues function normally, that the immune system is able to respond to infection, and that cell division and survival […]

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Is there a universal hierarchy of human senses?

Research at the University of York has shown that the accepted hierarchy of human senses—sight, hearing, touch, taste and smell—is not universally true across all cultures. Researchers found that rather than being able to predict the importance of the senses from biology, cultural factors were most important. Study revealed that cultures which placed particular value on their specialist musical heritage […]

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