Men and women have different genetic risk factors for developing brain cancer

Glioma is the most common type of primary malignant brain tumor in the United States; glioblastoma being the most common type of glioma in adults. While sex differences in the incidence and survival rates of glioma were known, researchers had not investigated whether genetic differences based on sex could cast light on potential differences in the risk profile of glioma […]

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Clostridium difficile infections have decreased 36 percent in Canadian hospitals

Rates of C. difficile infections have decreased 36% in hospitals across Canada, although the virulent NAP1 strain associated with severe illness and deaths is the most common strain, according to research published in CMAJ (Canadian Medical Association Journal) Clostridium difficile is the most common infectious cause of diarrhea in hospitalized patients in developed countries, causing severe illness and occasionally death. […]

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Older melanoma patients have better response to immune checkpoint blockade therapy

Patient age correlates with response to immunotherapy in melanoma and depleting regulatory T cells in young patients may have a therapeutic potential to enhance response in younger patients, according to research from The Wistar Institute. Study results were published online in Clinical Cancer Research. Immune checkpoint blockade therapy has been recently approved for treatment of melanoma based on its ability […]

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Children from older mothers more likely to have heart risks

New research published in The Journal of Physiology demonstrates that adult offspring born to older mothers are more susceptible to heart risks in later life. These results could be crucial in developing preventative treatments for children born to older women. Older motherhood is associated with an increased risk of complications during pregnancy with a greater likelihood of delivering a child […]

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Type 2 diabetes slowly rising in Auckland kids – Pacific and Māori have highest rates

New research shows increasing numbers of children and teens under-15 in Auckland are developing type 2 diabetes, and that rates among Pacific and Māori children are up to 18 times higher than for European children. The findings are based on 21 years of patient records from Starship Paediatric Diabetes Service. Says study lead Dr. Craig Jefferies: “People still don’t think […]

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More than one in 20 US children and teens have anxiety or depression

About 2.6 million American children and adolescents had diagnosed anxiety and/or depression in 2011-12, reports an analysis of nationwide data in the Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The number of children with diagnosed anxiety – but not depression – has increased in recent years, according to the new […]

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HCV-related liver transplantation and post-transplant survival rates in Europe have improved rapidly

HCV-related liver transplantation rates in Europe have declined dramatically since the availability of direct-acting antiviral (DAA) drugs and survival rates after transplantation have reached an all-time high. A study presented today at The International Liver Congress 2018 in Paris, France, has found that the percentage of liver transplants performed as a result of hepatitis C virus (HCV) infection has more […]

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