Penn gets $9.7 million grant to study concussion-related brain damage

Researchers from the University of Pennsylvania will lead an international team in a new project to study relationships between brain injuries and various types of neurodegeneration that lead to dementia symptoms. The work will be supported by a five-year, $9.7 million grant from the National Institute of Neurological Disorders and Stroke and the National Institute on Aging, Penn announced Thursday. […]

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IL-1 inhibitors may reduce radiation-induced vascular damage

Radiation therapy against cancer can increase the risk of cardiovascular disease much later in life, as the radiation causes chronic inflammation of the exposed blood vessels. In a new study published in the European Heart Journal, researchers from Karolinska Institutet in Sweden have shown that these inflammations can be treated with IL-1 inhibitors. Damage to healthy tissue is one of […]

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Researchers find targeting rare form of cystic fibrosis earlier prevents organ damage in ferrets

A team of researchers from the University of Iowa, University Medical Center Utrecht and Vertex Pharmaceuticals Incorporated, reports that earlier administration of a drug already given to patients with a rare form of cystic fibrosis can prevent organ damage—at least in ferrets. In their paper published in the journal Science Translational Medicine, the group describes their study of the impact […]

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Managing high blood pressure in diabetics may prevent life-threatening organ damage

The most effective way to prevent life-threatening complications of extreme hypertension in African-Americans with diabetes is to better control their blood pressure, according to a Rutgers study, the largest of its kind. The study, which appears in Clinical and Experimental Hypertension, included 783 diabetic and 1,001 non-diabetic patients from a New Jersey hospital emergency department that serves predominantly African-American communities. […]

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Hormone helps reverse brain damage caused by obesity

The neurobiotechnology research team of the Universitat Jaume I (UJI) in Castellón, Spain, headed by professor Ana María Sánchez, has proven the positive effects of a vegetable hormone, reversing brain alterations caused by high-fat diets, type-2 diabetes, obesity and physical inactivity. The results of this work, developed by the Health Sciences Department, have been published in Molecular Neurobiology. “We have […]

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New target could prevent progression of liver damage to cancer

Problems like obesity and alcoholism appear to chronically trigger in the liver a receptor known to amplify inflammation in response to invaders like bacteria, scientists report. The relentless, increased activity of TREM-1 in turn accelerates injury and scarring of the liver, a first step toward cirrhosis and liver cancer, says Dr. Anatolij Horuzsko, reproductive immunologist in the Georgia Cancer Center […]

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Research shows it’s possible to reverse damage caused by aging cells

What’s the secret to aging well? University of Minnesota Medical School researchers have answered it- on a cellular level. Aging starts in our cells, and those aging cells can hasten cellular senescence, leading to tissue dysfunction and related health impacts. New research involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer, recently published in Nature […]

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