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A team of scientists led by University of Montana cell biologist Mark Grimes has identified networks inside lung cancer cells that will help understand this cancer and fight it with drug treatments. The paper, published as the cover article of the May 22 issue of Science Signaling, sheds light on how a new class of drugs called HSP90 inhibitors—which are […]
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Josephine Rizo survived chemotherapy, surgery and radiation, but breast cancer treatment wrecked her finances. Money was already tight when doctors told the Phoenix resident she had an aggressive form of the disease. Then she took a pay cut after going on disability leave, and eventually lost her job and insurance coverage. During treatment, Rizo got swamped with more than $50,000 […]
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One strategy for cancer therapy is to inhibit the development of blood vessels in the tumour. Researchers at Uppsala University show in a new study how the protein CD93 interacts with the protein network that is required for tumour vessels to form properly. Blocking this interaction could be used as a means to hamper blood vessel development and slow down […]
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Though mutations in a gene called MLL3 are common across many types of cancers, their relationship to the development of the disease has been unclear. Now, a Northwestern Medicine study has identified an epigenetic imbalance that silences the expression of tumor-suppressing proteins, allowing cancerous cells to proliferate. In the study published in Nature Medicine, Northwestern investigators applied a simple molecular […]
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Anaplastic thyroid cancer is almost uniformly fatal, with an average lifespan of about 5 months after diagnosis. And standard treatment for the condition includes 7 weeks of radiation, often along with chemotherapy. “We put patients through toxic treatment for seven weeks when most will only live five months. I’m not sure that’s how I would want to spend my time,” […]
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Clinicians and researchers at Queen Mary University of London and the Homerton Hospital are encouraging black women to visit their GP if they notice any changes in their breasts. The call comes following the publication of a Queen Mary research paper which shows that among black women, breast cancer is often still perceived as “a disease of whiteness”. The study, […]
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(HealthDay)—A newer type of cancer treatment may offer the chance of longer survival, but the drugs could also trigger new side effects, such as vision problems. New research reports on three cases of a potentially vision-threatening eye condition called uveal effusion that patients developed after taking cancer immunotherapy. Immunotherapy uses a person’s own immune system to fight cancer. Uveal effusion […]
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A breath test can successfully detect oesophageal and gastric cancer and could be used as a first-line test for patients, say researchers. In a multi-centre clinical trial of 335 patients, the breath test can identify cancer from benign diseases with 85 per cent accuracy. Unlike other methods, the test is non-invasive. The study was led by researchers at Imperial College […]
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Polygenic risk scores could be useful to stratify the risk of several cancers among patients in medical centers, allowing for the potential discovery of new associations between genes, disease and secondary effects, according to a University of Michigan study. Researchers at U-M’s School of Public Health conducted a phenome-wide association study in 28,260 unrelated, genotyped patients of recent European ancestry […]
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Structural biologists at St. Jude Children’s Research Hospital have discovered how a key protein functions to trigger cell’s suicide machinery, called apoptosis. The scientists found that the protein, called BOK, is controlled separately from the rest of the apoptosis process—offering the potential for new drugs to more selectively kill cancer cells. Led by Tudor Moldoveanu, Ph.D., an assistant member of […]
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