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Small cell lung cancer (SCLC) accounts for 14 percent of all lung cancers and is often rapidly resistant to chemotherapy resulting in poor clinical outcomes. Treatment has changed little for decades, but a study at The University of Texas MD Anderson Cancer Center offers a potential explanation for why the disease becomes chemoresistant, and a possible avenue to explore new […]
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A phase I, first-in-human study led by The University of Texas MD Anderson Cancer Center reveals for the first time, an investigational drug that is effective and safe for patients with cancers caused by an alteration in the receptor tyrosine kinase known as RET. The drug appears to be promising as a potential therapy for RET-driven cancers, such as medullary […]
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A single treatment using an optimized, targeted form of faecal microbiota transplantation (FMT) produces sustained clinical and cognitive improvements, according to the results of a long-term follow-up of patients with liver cirrhosis and hepatic encephalopathy (HE) who had participated in a short-term study. The original, randomized, open label study, which enrolled 20 outpatient men with cirrhosis and recurrent HE receiving […]
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Patients with chronic hepatitis C virus (HCV) infection who achieve a sustained virological response (SVR) after direct-acting antiviral agent (DAA) treatment have lower all-cause mortality, according to a real-world study presented today at The International Liver Congress 2018 in Paris, France. The study, conducted in Italy, found that patients who achieved SVR were at reduced risk of death from both […]
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HCV-related liver transplantation rates in Europe have declined dramatically since the availability of direct-acting antiviral (DAA) drugs and survival rates after transplantation have reached an all-time high. A study presented today at The International Liver Congress 2018 in Paris, France, has found that the percentage of liver transplants performed as a result of hepatitis C virus (HCV) infection has more […]
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Researchers have found that more than one-third of patients who denied that their self-inflicted gunshot wound resulted from a suicide attempt most likely had indeed tried to kill themselves, and commonly were sent home from the hospital without further mental health treatment. The findings indicate there are significant barriers to treatment for people who have made suicide attempts, and highlight […]
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A new study to find a safer, efficacious and more patient-friendly treatment and improved diagnostic tools for people living with visceral leishmaniasis (VL) has begun in eastern Africa, within the new Afri-KA-DIA Consortium with funding from The European & Developing Countries Clinical Trials Partnership (EDCTP). The large-scale Phase III clinical trial seeks to assess the efficacy and safety of a […]
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Many people accept deteriorating eyesight as an inevitable part of getting older, but blurry or distorted vision – such as when straight lines appear wavy – could be signs of age-related macular degeneration. The condition is the most common cause of severe vision loss in people age 50 and older in developed countries. It occurs when waste products build up […]
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A researcher from James Cook University in Australia has found that a person’s mental state affects how they look at art. JCU psychology lecturer Nicole Thomas said the same piece of artwork can attract admiration or rejection from different people. “One intuitive explanation is that personality and the way in which we visually examine artwork contributes to our preferences for […]
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For J.R. Bourne, a day at the beach rekindles good and bad memories. It’s the place where the Jacksonville Beach, Florida, resident died and was brought back to life thanks to fast-thinking first responders and an automated external defibrillator. Back in June 2015, then-40-year-old Bourne was playing soccer on the beach with his friend Luis when he suddenly collapsed and […]
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