New mathematical parameters to model the impact of Wolbachia infection for disease control

LSTM’s Dr. Gabriela Gomes is senior author on a new study which outlines the importance of using variation in mosquito susceptibility as a parameter in mathematical modelling to realistically assess the impact of Wolbachia infection on disease transmission. The Aedes aegypti mosquito is a disease vector for a number of arboviruses including, chikungunya, dengue and Zika. Wolbachia, a bacterial symbiont, […]

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Mechanism that drives development of liver cancer brought on by non-alcoholic fatty liver disease discovered

A team of researchers from several institutions in China has found a mechanism that appears to drive the development of a type of liver cancer not caused by alcohol consumption. In their paper published in the journal Science Translational Medicine, the group describes their study of liver cancer in mouse models and what they found. Ngee Kiat Chua, Hudson Coates […]

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Can early counselling prevent post traumatic stress induced by heart attacks?

A randomized controlled trial published in the current issue of Psychotherapy and Psychosomatics indicates that early counseling has a very limited role in preventing distress after heart attacks. Acute coronary syndrome (ACS)-induced posttraumatic stress disorder (PTSD) and clinically significant PTSD symptoms are found in 4 and 12 percent of patients, respectively. Hence, this randomized-controlled trial aimed to test whether early […]

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Can fish oil supplementation attenuate stress symptoms in high risk jobs?

A study published in the current issue of Psychotherapy and Psychosomatics suggests a role for fish-oil supplementation in workers who perform very stressful jobs. There is growing attention being paid to fish oil as one of the promising supplementations to improve symptoms of posttraumatic stress disorder (PTSD) by facilitating hippocampal neurogenesis and clearance of fear memory. The purpose of this […]

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How environmental pollutants and genetics work together in rheumatoid arthritis

It has been known for more than three decades that individuals with a particular version of a gene—human leukocyte antigen (HLA)—have an increased risk for rheumatoid arthritis. Meanwhile, in recent years, there has been a growing interest in the relationship between rheumatoid arthritis and environmental factors, such as cigarette smoking. In smokers who develop rheumatoid arthritis, the disease hits harder. […]

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Gene twist can make your blood pressure spike from salt

(HealthDay)—New research sheds light on why some people’s blood pressure is especially sensitive to salt. The research team previously discovered that a natural gene variation that occurs in 48 percent of people increases a person’s chances of having blood pressure that’s sensitive to salt. Their new study revealed how this gene variant prevents the body from eliminating excess salt. The […]

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Self-regulation interventions beneficial for children

(HealthDay)—A range of interventions can successfully improve self-regulation in children and adolescents, according to research published online April 16 in JAMA Pediatrics. Anuja Pandey, M.D., from the University College London Great Ormond Street Institute of Child Health, and colleagues conducted a systematic review and meta-analysis of rigorously evaluated interventions to improve self-regulation in children and adolescents. The final review included […]

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An artificial mole as an early warning system

Alongside cardiovascular disease, cancer has become the top cause of death in industrialised countries. Many of those affected are diagnosed only after the tumour has developed extensively. This often reduces the chance of recovery significantly: the cure rate for prostate cancer is 32 percent and only 11 percent for colon cancer. The ability to detect such tumours reliably and early […]

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