Restoring protein homeostasis improves memory deficits in Down syndrome model

Down syndrome is the most common genetic cause of intellectual disability, and currently there is no effective treatment. Memory deficits are a hallmark of this condition and a study published today in the journal Science reports that the defects in a conserved stress pathway dubbed the ‘integrated stress response,’ or ISR, could explain the cognitive deficits in a mouse model […]

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Zika virus can cause immune and brain abnormalities in asymptomatic pig offspring

Zika virus infection in the womb produces altered immune responses and sex-specific brain abnormalities in apparently healthy pig offspring, according to a study published november 14 in the open-access journal PLOS Pathogens by Uladzimir Karniychuk of the University of Saskatchewan, and colleagues. As noted by the authors, the findings could point to new strategies to prevent and alleviate the long-term […]

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How maternal Zika virus infection results in newborn microcephaly

A new study led by researchers at Baylor College of Medicine revealed how in utero Zika virus infection can lead to microcephaly in newborns. The team discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons. The findings point at the possibility of developing therapeutic strategies to prevent microcephaly […]

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Study: Multidisciplinary transplantation evaluation shows promise for older adults

Older adults with blood cancers can benefit from a team-based, holistic evaluation before undergoing transplantation, according to a new study published today in Blood Advances. The study, which reported on a multidisciplinary clinic (MDC) at the University of Chicago Medical Center, found that patients treated with this approach experienced better transplantation outcomes and survival rates. Most blood cancers that can […]

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Second Ebola vaccine introduced in DR Congo

Authorities in the Democratic Republic of Congo Thursday introduced a second vaccine to fight the deadly Ebola virus in the east of the country, the Doctors Without Borders (MSF) charity said. It said the new vaccine, produced by a Belgian subsidiary of Johnson & Johnson, is aimed at protecting about 50,000 people over a period of four months. More than […]

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Storytellers for children: Jawaharlal Nehru

Jawaharlal Nehru birth anniversary: The former Prime Minister wrote several books that have been lauded as records of his life, the freedom struggle and an explication of his vision for independent India. (This is the second in a series on iconic storytellers for children.) By Deepa Agarwal Jawaharlal Nehru’s love for children is so legendary that his birthday, November 14, […]

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Watch Kelly Clarkson's Kids Remy, 3½, and River, 5, Adorably Grill Jason Momoa About Aquaman

Kelly Clarkson‘s little Aquaman fans have a few fish bones to pick with its star, Jason Momoa. The actor — who will reprise his titular role in the 2018 DC Comics film’s upcoming sequel — stopped by Clarkson’s daytime talk show on Wednesday, where he was joined by the host’s son Remington “Remy” Alexander, 3½, and daughter River Rose, 5, for a […]

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Neuroscientists have gained new insight into how the brain predicts missing visual information

Neuroscientists at the University of Glasgow have gained new insight into how the brain predicts missing visual information when perceiving the outside world. The researchers, from the University’s Institute of Neuroscience and Psychology, discovered that our brains “sketch out” portions of scenes that are not visible—much like how an artist sketches out a scene before filling the remaining details. The […]

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