Risk of cochlear disorders up with history of migraine

(HealthDay)—The risk of cochlear disorders, especially tinnitus, is increased among patients with a history of migraine, according to a study published online July 12 in JAMA Otolaryngology-Head & Neck Surgery.

Juen-Haur Hwang, M.D., Ph.D., from the Dalin Tzu Chi Hospital in Taiwan, and colleagues used claims data from the Taiwan Longitudinal Health Insurance Database 2005 to identify 1,056 patients with migraines. Based on propensity score matching, 4,224 controls were identified from the same database.

The researchers found that the crude hazard ratio for cochlear disorders was 2.83 (95 percent confidence interval [CI], 2.01 to 3.99) in the migraine cohort compared with the non-migraine cohort; the adjusted hazard ratio was 2.71 (95 percent CI, 1.86 to 3.93). For the migraine and non-migraine cohorts, the incidence rates of cochlear disorders were 81.4 and 29.4 per one million person-years, respectively. The cumulative incidence of cochlear disorders was significantly higher in the migraine versus the matched non-migraine cohort (12.2 versus 5.5 percent). In subgroup analysis, the adjusted hazard ratios in the migraine cohort versus the non-migraine cohort were 3.30 (95 percent CI, 2.17 to 5.00) for tinnitus, 1.03 (95 percent CI, 0.17 to 6.41) for sensorineural hearing impairment, and 1.22 (95 percent CI, 0.53 to 2.83) for sudden deafness.

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