Childhood leukemia cannot hide from the immune system

St. Jude Children’s Research Hospital scientists have evidence that children with acute lymphoblastic leukemia mount a robust immune response to their cancer. The findings, which appear today in the journal Science Translational Medicine, will likely aid development of immunotherapy for the most common childhood cancer. Immunotherapy has revolutionized cancer treatment in the last decade, particularly for adults with melanoma, lung […]

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Infrared imaging technology being developed to better detect breast cancer

Researchers have found a non-invasive, cost effective method that uses infrared technology to locate hard-to-find breast cancer tumors. For the 40-50% of women with dense breast tissue, where these tumors often hide, this technology could be the difference between early interventions or major surgery. Faculty and student researchers at Rochester Institute of Technology, and physicians from the Rochester Regional Health […]

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Could prosthetic limbs one day be controlled by human thought?

For almost two decades, Stanford electrical engineering professor Krishna Shenoy and neuroscientists in his Neural Prosthetics Translational Laboratory have been working on implantable brain sensors that allow them to record and decipher the electrical activity of neurons that control body movement. The long-term goal: to build prosthetics that amputees and those with paralysis can control with their thoughts. Currently, the […]

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Boosting the cancer-destroying ability of killer T-cells

More types of cancer could potentially be destroyed by patients’ own immune cells, thanks to new research by Cardiff University. The team of researchers discovered that increasing the amount of the molecule L-selectin on T-cells can vastly improve their ability to fight solid tumors. Professor Ann Ager, from Cardiff University’s Systems Immunity Research Institute, said: “These results mean that immunotherapy […]

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New target for drug intervention in Alzheimer’s disease identified

Scientists at the University of Alabama at Birmingham have identified an enzyme in the brain that may be an intriguing target for interventions against Alzheimer’s disease and other dementias. The researchers suggest that the enzyme, a serine/threonine kinase known as LIMK1, may play an important role in the degradation of dendritic spines, the connections between neurons in the brain. In […]

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NIH launches large TB prevention trial for people exposed to multidrug-resistant TB

A large clinical trial to assess treatments for preventing people at high risk from developing multidrug-resistant tuberculosis (MDR-TB) has begun. The study is comparing the safety and efficacy of a new MDR-TB drug, delamanid, with the decades-old TB drug isoniazid for preventing active MDR-TB disease in children, adolescents and adults at high risk who are exposed to adult household members […]

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Lifelong ill-health after exposure to chemical weapons

People exposed to chemical warfare agents (CWAs) often incur chronic damage to their lungs, skin and eyes, for example. They also frequently succumb to depression, anxiety and suicidal thoughts. This is shown by research on survivors from the 1988 gas attacks against Kurdish Halabja in Iraq. “The findings show that exposure to chemical warfare agents, especially sulfur mustard, results in […]

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Criteria for bariatric surgery should consider more than just patient’s weight

Experts at the Ohio State University Wexner Medical Center and 45 worldwide scientific and medical societies are pushing to change national guidelines that would allow more patients with the chronic diseases of obesity and diabetes to be eligible for bariatric surgery. Obesity affects almost 40 percent of the population—or about 93 million adults—in the United States, according to the Centers […]

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