Wearable and implantable devices may transform care for patients with kidney failure

A feature article appearing in an upcoming issue of CJASN highlights the potential of wearable and implantable devices for treating kidney failure. In their feature article, Shuvo Roy, Ph.D. (University of California, San Francisco) and his colleagues note that traditional hemodialysis performed in clinics has a number of shortcomings, with patients reporting burdens related to fatigue, poor sleep, inability to […]

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Practical Steps to Prevent Diabetes

So, do you want to hear the good news or the bad news first? Okay, here’s the bad news—type 2 diabetes is on the rise in the United States, with more than 100 million adults living with diabetes or prediabetes, according to a 2017 Centers for Disease Control and Prevention report. The good news? Type 2 diabetes can be prevented […]

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Restoring protein homeostasis improves memory deficits in Down syndrome model

Down syndrome is the most common genetic cause of intellectual disability, and currently there is no effective treatment. Memory deficits are a hallmark of this condition and a study published today in the journal Science reports that the defects in a conserved stress pathway dubbed the ‘integrated stress response,’ or ISR, could explain the cognitive deficits in a mouse model […]

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Zika virus can cause immune and brain abnormalities in asymptomatic pig offspring

Zika virus infection in the womb produces altered immune responses and sex-specific brain abnormalities in apparently healthy pig offspring, according to a study published november 14 in the open-access journal PLOS Pathogens by Uladzimir Karniychuk of the University of Saskatchewan, and colleagues. As noted by the authors, the findings could point to new strategies to prevent and alleviate the long-term […]

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How maternal Zika virus infection results in newborn microcephaly

A new study led by researchers at Baylor College of Medicine revealed how in utero Zika virus infection can lead to microcephaly in newborns. The team discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons. The findings point at the possibility of developing therapeutic strategies to prevent microcephaly […]

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Study: Multidisciplinary transplantation evaluation shows promise for older adults

Older adults with blood cancers can benefit from a team-based, holistic evaluation before undergoing transplantation, according to a new study published today in Blood Advances. The study, which reported on a multidisciplinary clinic (MDC) at the University of Chicago Medical Center, found that patients treated with this approach experienced better transplantation outcomes and survival rates. Most blood cancers that can […]

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Second Ebola vaccine introduced in DR Congo

Authorities in the Democratic Republic of Congo Thursday introduced a second vaccine to fight the deadly Ebola virus in the east of the country, the Doctors Without Borders (MSF) charity said. It said the new vaccine, produced by a Belgian subsidiary of Johnson & Johnson, is aimed at protecting about 50,000 people over a period of four months. More than […]

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Neuroscientists have gained new insight into how the brain predicts missing visual information

Neuroscientists at the University of Glasgow have gained new insight into how the brain predicts missing visual information when perceiving the outside world. The researchers, from the University’s Institute of Neuroscience and Psychology, discovered that our brains “sketch out” portions of scenes that are not visible—much like how an artist sketches out a scene before filling the remaining details. The […]

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When do children begin to recognize hypocrisy?

Practice what you preach. Suit your actions to your words. Walk the talk. Hypocrisy is ingrained as a moral failing for most adults, but when do children learn to make the same distinction? According to a new study from University of Chicago psychologists, the shift seems to happen early in elementary school. The researchers discovered that children who were at […]

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