Obesity may hasten disability in patients with rheumatoid arthritis

In a study of adults with rheumatoid arthritis, those who were severely obese experienced more rapidly progressing disability than patients who were overweight. This was not explained by features of their arthritis, including the amount of inflammation in their joints. In the Arthritis Care & Research study, weight loss after enrollment was also associated with worsening disability, possibly as a […]

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Study shows a new approach to treating patients with stage IV Wilms tumor

A new study showing significantly improved survival rates for patients with stage IV Wilms tumors with lung metastases was recently published in the Journal of Clinical Oncology. The outcomes of the study, “Treatment of Stage IV Favorable Histology Wilms Tumor With Lung Metastases: A Report From the Children’s Oncology Group AREN0533 Study”, will be a game-changer in treating Wilms tumor […]

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New rules on saving kids stricken with cardiac arrest

Saving a child with heart disease whose heart has stopped requires a different approach than reviving a child with a healthy heart, according to a new scientific statement from the American Heart Association. Cardiac arrest in the hospital is 10 times more common among children with congenital heart defects or other acquired heart conditions compared to children with healthy hearts, […]

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A study links soil metals with cancer mortality

Spanish epidemiologists and geologists have found associations between esophageal cancer and soils where lead is abundant. Lung cancer has been associated with high copper content in soil; brain tumors are linked with areas rich in arsenic, and bladder cancer is associated with high cadmium levels. These statistical links do not indicate that there is a cause-effect relationship between soil type […]

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Pathways in the young brain are associated with susceptibility for mental disorders

Adolescence is a period for individual growth and opportunities, but it also coincides with the emergence of many mental disorders. In a study that was recently published in JAMA Psychiatry, Norwegian researchers revealed that the pathways between brain regions are associated with early signs of mental illness in youth. The researchers analyzed a wide range of clinical, cognitive, and genetic […]

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Efficient control of leukaemia with treatment by dual immune-checkpoint blockade

Chronic lymphocytic leukaemia (CLL) is a haematological malignancy that originates in the blood-forming cells of the bone marrow and spreads to other organs through the bloodstream. When infiltrating tissues, CLL cells come in contact with healthy cells, including immune cells. To ensure their survival and growth, CLL cells are able to establish a microenvironment in which the immune response is […]

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Metabolic syndrome common with chronic hep B infection

(HealthDay)—Metabolic syndrome (MetS) is prevalent among patients with chronic hepatitis B (HBV) infection, according to a study published online March 29 in Diabetes Care. Mandana Khalili, M.D., from the University of California, San Francisco, and colleagues assessed prevalence of MetS and its influence on alanine aminotransferase (ALT) levels and fibrosis among a multiethnic North American cohort with chronic HBV infection […]

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