TAILORx trial finds most women with early breast cancer do not benefit from chemotherapy

New findings from the groundbreaking Trial Assigning Individualized Options for Treatment (Rx), or TAILORx trial, show no benefit from chemotherapy for 70 percent of women with the most common type of breast cancer. The study found that for women with hormone receptor (HR)-positive, HER2-negative, axillary lymph node¬-negative breast cancer, treatment with chemotherapy and hormone therapy after surgery is not more […]

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Study of acute myeloid leukemia patients shows protein inhibitor drug safe and effective with durable remissions

Ivosidenib, an experimental drug that inhibits a protein often mutated in several cancers has been shown to be safe, resulting in durable remissions, in a study of acute myeloid leukemia (AML) with relapsed or refractory disease. The multi-center Phase I trial, led by researchers at The University of Texas MD Anderson Cancer Center, was designed to determine ivosidenib’s safety and […]

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T1DM self-management varies with adult developmental stages

(HealthDay)—Type 1 diabetes self-management behaviors vary across adult developmental stages, according to a study published online May 25 in Diabetes Care. Margaret M. McCarthy, Ph.D., from the New York University Rory College of Nursing in New York City, and Margaret Grey, Dr.P.H., R.N., from the Yale School of Nursing in Orange, Conn., examined patterns of diabetes self-management behaviors and predictors […]

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Conflicting guidance on opioid prescribing can jeopardize pain management for patients with cancer

Persistent pain and recurrent episodes of pain are common for those who are living with cancer, or for those undergoing cancer treatment. When used properly, prescription opioids have long been known to help combat pain experienced by people with cancer. In the face of the worsening opioid epidemic, clinical guidelines have been published by multiple agencies to improve the way […]

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Researchers magnify the brain in motion with every heartbeat

Understanding how the brain moves—at rest and upon impact—has been crucial to understanding brain disorders, but technology to clearly see these movements has lagged behind. Now, researchers from Stevens Institute of Technology, in collaboration with University of Auckland and Stanford University, have developed an imaging technique that captures and magnifies the brain in motion, in real time, every time the […]

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High protein diet associated with small increased heart failure risk in middle-aged men

For middle-aged men, eating higher amounts of protein was associated with a slightly elevated risk for heart failure than those who ate less protein, according to new research in Circulation: Heart Failure, an American Heart Association journal. Despite the popularity of high protein diets, there is little research about how diets high in protein might impact men’s heart failure risk. […]

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Women with pregnancy-related diabetes may be at risk for chronic kidney disease

Gestational diabetes may predispose women to early-stage kidney damage, a precursor to chronic kidney disease, according to a study by researchers at the National Institutes of Health and other institutions. The study appears in Diabetes Care. Gestational diabetes occurs only in pregnancy and results when the level of blood sugar is too high. The condition increases the risk for preterm […]

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