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Tattoos have become more common and more acceptable in today’s society, as more and more people are opting to get inked. Many claim that it has to do with celebrities and mainstream influencers flaunting ink on social media and putting it in the spotlight (via Byrdie). However, getting a tattoo is a serious commitment. Sometimes, people aren’t 100% sure about what […]
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It’s his day! Prince Harry and Meghan Markle wanted their son, Archie, to feel heaps of love on his 2nd birthday — and his last before he’s a big brother. Inside Prince Harry, Meghan Markle’s Parenting Style Raising Son Archie “While Harry and Meghan are raising Archie to be grounded, they go the extra mile on his birthday,” a source […]
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A new era of Billie Eilish has officially begun. We've known it was coming since the moment she swapped her signature black-and-green hair for platinum blonde and began teasing new music — but a new cover shoot with British Vogue shows just how much the singer has evolved. On May 2, Eilish revealed via Instagram that she is the star […]
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With CAR T cell therapy, a patient’s own immune cells are genetically modified and inserted back into the body to find and kill cancer. This form of immunotherapy has already revolutionized some cancer treatments, but once the CAR T cells are inside a patient, where do they go? How do doctors know that they have successfully reached their target and […]
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The advent and advancement of T cell therapy, especially chimeric antigen receptor (CAR)-modified T cells, has demonstrated therapeutic potential in treating previously treatment-resistant tumors. However, few CAR targets are absolutely tumor-specific, resulting in “on-target, off-tumor” toxicities that can be severe. Researchers in the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist […]
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The doctors who have spent years studying the case call it “a series of fortunate events.” What began as a remarkable response to chimeric antigen receptor (CAR) T cell therapy is now providing evidence about the human genome and immune response that could help turn gene therapy non-responders into responders. Researchers at the University of Pennsylvania’s Abramson Cancer Center say […]
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The U.S. Food and Drug Administration (FDA) has expanded approval for a personalized cellular therapy developed at the University of Pennsylvania’s Abramson Cancer Center, this time for the treatment of adult patients with relapsed or refractory large B-Cell lymphoma after two or more lines of systemic therapy. Today’s approval includes treatment of diffuse large B-cell lymphoma (DLBCL) – the most […]
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Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia (CLL) don’t respond to chimeric antigen receptor (CAR) T cell therapy, and the answer is tied to how primed patients’ immune systems are before the therapy is administered. While 80 percent of patients with advanced acute lymphoblastic leukemia (ALL) treated with the CAR T […]
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As immunotherapies continue to make up a larger share of new cancer drugs, researchers are looking for the most effective ways to use these cutting edge treatments in combination with each or with other pre-existing options. New studies from the Abramson Cancer Center of the University of Pennsylvania are providing fresh clues on potentially effective combinations with CAR T therapy […]
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