100-year-old scientific mystery solved: Researchers discover role of nuclear glycogen in non-small cell lung cancers

Health Problems

Researchers at the University of Kentucky Markey Cancer Center have made a breakthrough discovery that solves a mystery long forgotten by science and have identified a potentially novel avenue in pre-clinical models to treat non-small cell lung cancers. Published in Cell Metabolism, the research centers on the function of glycogen accumulation in the nucleus of a cell. Glycogen is known […]

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Genetic ‘whodunnit’ for cancer gene solved

Health Problems

Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, Salk Institute researchers have solved the long-standing mystery around why AMPK can both hinder and help cancer. The lab of Salk Professor Reuben Shaw showed that late-stage cancers can trigger AMPK’s cellular recycling signal to cannibalize pieces […]

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Family blood mystery solved

Health Problems

In the late 1970s, a man with an unexplained high hemoglobin level (Hb) was referred to Namsos Hospital north of Trondheim, Norway. It turned out that four members of his family had the same condition. Doctor Kjell Kanelønning was the physician who treated the family. He examined the man and his family members thoroughly without finding the cause of their […]

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