Long-term prognosis of Chagas patients improved with anti-parasite drug

Researchers have found that the anti-parasite drug benznidazole may improve the long-term prognoses of patients with chronic Chagas disease, according to a study published in PLOS Neglected Tropical Diseases, by Clareci Silva Cardoso at the Federal University of São João del-Rei, Divinópolis, Brazil, and colleagues from the SaMi-Trop study, a project funded by NIAID/NIH. Caused by exposure to the protozoa […]

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New drug slashes death rates among drug-resistant TB patients: scientists

Credit: CC0 Public Domain A new treatment for a deadly drug-resistant strain of tuberculosis can cure more than 90 percent of sufferers, according to a landmark clinical trial whose results were revealed exclusively to AFP. Doctors in Belarus—a country with one of the world’s highest rates of multidrug-resistant tuberculosis—treated 181 patients with the new drug, bedaquiline, in combination with other […]

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Cancer patients with rare deadly brain infection treated successfully with off-the-shelf adoptive T-cell therapy

An emerging treatment known as adoptive T-cell therapy has proven effective in a Phase II clinical trial for treating progressive multifocal leukoencephalopathy (PML), a rare and often fatal brain infection sometimes observed in patients with cancer and other diseases in which the immune system is compromised. The study, led by Katy Rezvani, M.D., Ph.D., professor, Department of Stem Cell Transplantation […]

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Liver transplant, weight-loss surgery combination benefits obese patients in long term

Obese patients who underwent a life-saving liver transplant and weight-loss surgery at the same time were better able to keep the weight off long term and had fewer metabolic complications than those who lost weight on their own before undergoing a liver transplant, Mayo Clinic research shows. The findings were recently published in Hepatology. “This study shows that the combined […]

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Triple dual therapy significantly improves lung function, quality of life in COPD patients

The InforMing the PAthway of COPD Treatment (IMPACT) study was conducted to assess the benefits of triple versus dual therapy in patients with COPD. In a study at CHEST, researchers found that regardless of baseline reversibility, the usage of triple dual therapies significantly reduced the annual rate and moderate-to-severe and severe exacerbations, improved lung function and overall quality of life […]

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A behavioral intervention for cancer patients that works

This is a story about something rare in health psychology: a treatment that has gone from scientific discovery, through development and testing, to dissemination and successful implementation nationwide. In a new study, researchers found that a program designed at The Ohio State University to reduce harmful stress in cancer patients can be taught to therapists from around the country and […]

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Patients with sepsis at higher risk of stroke, heart attack after hospital discharge

Patients with sepsis are at increased risk of stroke or myocardial infarction (heart attack) in the first 4 weeks after hospital discharge, according to a large Taiwanese study published in CMAJ (Canadian Medical Association Journal). Sepsis accounts for an estimated 8 million deaths worldwide, and in Canada causes more than half of all deaths from infectious diseases. Researchers looked at […]

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Patients with new-onset AFib after TAVR at highest risk for complications

Patients developing AFib after TAVR are at higher risk of death, stroke and heart attack compared to patients who already had AFib prior to the procedure, according to a study today in JACC: Cardiovascular Interventions. The paper is the first nationwide examination of patients who developed AFib for the first time following TAVR. Transcatheter aortic valve replacement (TAVR) is a […]

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