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A novel technological approach developed by researchers at Baylor College of Medicine expands from two to six the number of molecular pathways that can be studied simultaneously in a cell sample with the dual luciferase assay, a type of testing method commonly used across biomedical fields. Published in the journal Nature Communications, the report shows that multiplexed hextuple luciferase assaying, […]
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A team of scientists led by University of Montana cell biologist Mark Grimes has identified networks inside lung cancer cells that will help understand this cancer and fight it with drug treatments. The paper, published as the cover article of the May 22 issue of Science Signaling, sheds light on how a new class of drugs called HSP90 inhibitors—which are […]
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Researchers from the Albert Einstein College of Medicine in New York have discovered that a signaling protein elevated in patients with acute myeloid leukemia (AML) plays a much wider role in the disease than previously thought. The study, which will be published May 17 in the Journal of Experimental Medicine, raises hopes that current efforts to target this signaling protein […]
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Adolescence is a period for individual growth and opportunities, but it also coincides with the emergence of many mental disorders. In a study that was recently published in JAMA Psychiatry, Norwegian researchers revealed that the pathways between brain regions are associated with early signs of mental illness in youth. The researchers analyzed a wide range of clinical, cognitive, and genetic […]
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