Insulin Resistance and Parkinson's Disease

A growing pool of evidence suggests that Type 2 diabetes mellitus (T2DM) and Parkinson’s disease (PD) may share common pathological mechanisms, and that the presence of T2DM increases the risk of developing PD by 40%. Measuring blood sugar level. Image Credit: Neirfy / Shutterstock How is T2DM Connected to PD? PD, the second most common neurodegenerative disorder after Alzheimer’s disease, […]

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What is CRIA syndrome?

Skip to: Symptoms & Pathology Causes and Current Research Treatment Cleavage-resistant RIPK1-induced autoinflammatory (CRIA) syndrome, is a recently discovered autoinflammatory disease caused by mutations within the receptor-interacting serine/threonine-protein kinase 1 (RIPK1) gene. The exact prevalence of CRIA syndrome is still undetermined as it has only recently been identified as a disease. Seven people from three separate families in the U.S. […]

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Does Depression and Anxiety Increase the Risk of Dementia?

Skip to: Can Depression Increase the Risk of Dementia? Can Anxiety Increase the Risk of Dementia? Depression and anxiety can affect individuals across their life-course whereas dementia tends to typically affect older people. Depression and anxiety are common symptoms of dementia, but much less is known about whether depression and anxiety can actually lead to dementia. Image Credit: Photographee.eu / […]

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Brestoff, Theunissen recognized by NIH for innovative research

Obesity expert Jonathan R. Brestoff, MD, PhD, and regenerative medicine specialist Thorold Theunissen, PhD, both of Washington University School of Medicine in St. Louis, have received High-Risk, High-Reward Research awards from the National Institutes of Health (NIH). The program supports scientists showing exceptional creativity and pursuing innovative research programs with the potential to have a wide impact in biomedical, behavioral […]

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Rhesus macaque model offers route to study Zika brain pathology

Rhesus macaque monkeys infected in utero with Zika virus develop similar brain pathology to human infants, according to a report by researchers at the California National Primate Research Center and School of Veterinary Medicine at the University of California, Davis, published June 20 in Nature Communications. Rhesus macaques may be a suitable model system to study how Zika virus infection […]

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New rapid-fire method using pathology images, tumor data may help guide cancer therapies

By combining data on pathology images of 13 types of cancer and correlating that with clinical and genomic data, a Stony Brook University-led team of researchers are able to identify tumor-infiltrating lymphocytes (TILs), called TIL maps, which will enable cancer specialists to generate tumor-immune information from routinely gathered pathology slides. Published in Cell Reports , the paper details how TIL […]

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