Researchers write ABCs of language disorder

While we expect to see scientists publishing in journals aimed at peers, a pair of Western researchers recently targeted a younger audience for their work—a lot younger. Reviewers for their newest scholarly paper, “Developmental Language Disorder: The Childhood Condition We Need to Talk About,” are ages 8, 10 and 13. When not reviewing science papers for Frontiers for Young Minds, […]

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How DNA outside cells can be targeted to prevent the spread of cancer

Cell-free DNA (cfDNA) is DNA found in trace amounts in blood, which has escaped degradation by enzymes. Scientists from Tokyo University of Science, led by Prof Ryushin Mizuta, have now discovered exactly how cfDNA is generated. They also talk about the applications of DNase1L3—the enzyme mainly responsible for generating cfDNA—as a novel molecule to prevent the spread of tumors. Prof […]

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Uncovering possible role of polyphosphate in dialysis-related amyloidosis

Long-term dialysis treatment is tough on the body in many ways, but one of the most serious complications is dialysis-related amyloidosis, a disease characterized by abnormal buildup of protein aggregates—called amyloid fibrils—in joints, tissues and organs. Although there is no cure, recent research by Osaka University researchers sheds light on how amyloid fibrils form and aggregate, thereby allowing the identification […]

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Microvascular disease anywhere in the body may be linked to higher risk of leg amputations

Microvascular disease is independently associated with a higher risk of leg amputation compared to people without the disease, according to new research in the American Heart Association’s journal Circulation. The study, funded by the American Heart Association Strategically Focused Research Network in Vascular Disease and the U.S. Department of Veterans Affairs, examined amputation risk among people with microvascular disease or […]

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New research suggests three profiles of communication delays in early childhood

Parenting books, magazines and apps are filled with tools to help parents keep track of their child’s developmental milestones. Parents are often particularly concerned about their child’s language and communication skills. But what does it mean if your child doesn’t meet these early milestones? New research published in the Journal of Developmental and Behavioral Pediatrics suggests that repeated delays in […]

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Seven-country study reveals viruses as new leading cause of global childhood pneumonia

Respiratory syncytial virus (RSV) and other viruses now appear to be the main causes of severe childhood pneumonia in low- and middle-income countries, highlighting the need for vaccines against these pathogens, according to a study from a consortium of scientists from around the world, led by a team at the Johns Hopkins Bloomberg School of Public Health. Pneumonia is the […]

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Researchers criticize study calling for expansion of genetic testing for breast cancer

Researchers at the University of Cambridge have criticised a recent study calling into question guidelines on genetic testing for hereditary breast cancer. In an article published in the Journal of Clinical Oncology in December 2018 entitled “Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle?”, 27 US researchers argued for expanded genetic testing in all […]

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Rapid spread of a meningitis bacteria linked to hypermutable sequences helping avoidance of the immune system

An enhanced potential to avoid the human immune system has been found in recent serogroup W isolates of Neisseria meningitidis by University of Leicester researchers, which may explain in part why the strain spread so rapidly among young people in 2013. The study, published last week in the Journal of Infectious Diseases, saw researchers from Leicester, the University of Nottingham […]

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