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Most neurons in the human brain are generated from neural stem cells during embryonic development. After birth, a small reservoir of stem cells remain in the brain that keeps on producing new neurons throughout life. However, the question arises as to whether these new neurons really support brain function? And if so, can we improve brain capacity by increasing the […]
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UCLA and UC San Francisco life scientists have discovered a dramatic pattern of bone growth in female mice—research that could potentially lead to stronger bone density in women and new treatments for osteoporosis in older women. The researchers found that blocking a particular set of signals from a small number of neurons in the brain causes female, but not male, […]
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Immunotherapies that take off the “brakes” on the adaptive anti-tumor response have worked well in melanoma and lung cancer but less so in breast cancers. That could change. A Vanderbilt team led by John Wilson, assistant professor of chemical and biomolecular engineering, and Rebecca Cook, associate professor of cell and developmental biology, activated innate immunity in breast cancer cells and […]
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There are hundreds of metabolic disorders—including phenylketonuria, tyrosinemia, maple syrup urine disease and homocystinuria. These disorders lead to congenital diseases that produce a critical enzyme deficiency that interferes with the body’s metabolism. The pathologies and symptoms vary among the diseases, but all of them are usually fatal and have no known cure. Most metabolic disorders affect infants. The majority of […]
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A clot in the retinal vein can lead to severe and irreversible loss of vision. In a report in the American Journal of Pathology investigators utilize a newly developed model of central retinal vein occlusion (CRVO) in mice that mimics many of the clinical features of CRVO in humans to study the pathologic effects of retinal occlusion and demonstrate the […]
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Researchers from Queen’s University Belfast, in collaboration with the University of Bristol, are leading a cutting-edge project, named the “MONARCH” study, that could benefit eye disease patients whilst saving both time and money within the NHS. The MONARCH study aims to investigate if patients with an eye condition called wet age-related macular degeneration (AMD) could test their vision at home, […]
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Christmas is supposed to be a magical time. The season is full of gifts, bright lights, family, friends and food, and sentimentality. It brings back memories of days long since passed. But for parents? Well, for parents the Christmas season can be stressful. Scratch that: It can be hella hard because we are all trying to live up to some impossible ideal […]
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The Paleoneurobiology group of the Centro Nacional de Investigación sobre la Evolución Humana (CENIEH), led by Emiliano Bruner, has just published, in collaboration with the Museo de la Evolución Humana (MEH) in Burgos and the company Sociograph from Valladolid, a new paper on cognitive archaeology in which the hand-tool relationship is studied, analyzing the geometry of the tools, the grasp […]
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Scientists at the University of York have developed a new technique that uses light to understand how cells communicate in human disease. All cells in the human body communicate with each other by releasing signalling molecules; this helps to ensure that tissues function normally, that the immune system is able to respond to infection, and that cell division and survival […]
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An updated guideline on screening for breast cancer emphasizes shared decision-making between women and their doctors, supporting women to make an informed decision based on personal preferences when the balance between benefits and harms is uncertain. The guideline, released by the Canadian Task Force on Preventive Health Care, is published in CMAJ (Canadian Medical Association Journal). Based on the latest […]
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