New knowledge on the development of asthma

Researchers at Karolinska Institutet in Sweden have studied which genes are expressed in overactive immune cells in mice with asthma-like inflammation of the airways. Their results, which are published in the journal Immunity, suggest that the synthesis and breakdown of fats plays an important part in the process. The job of the human immune system is to read our environment […]

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New target for drug intervention in Alzheimer’s disease identified

Scientists at the University of Alabama at Birmingham have identified an enzyme in the brain that may be an intriguing target for interventions against Alzheimer’s disease and other dementias. The researchers suggest that the enzyme, a serine/threonine kinase known as LIMK1, may play an important role in the degradation of dendritic spines, the connections between neurons in the brain. In […]

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New framework helps gauge impact of mosquito control programs

Effective methods of controlling mosquito populations are needed to help lower the worldwide burden of mosquito-borne diseases including Zika, chikungunya, and dengue. Now, researchers reporting in PLOS Neglected Tropical Diseases have described a new statistical framework that can be used to assess mosquito control programs over broad time and space scales. The mosquito Aedes aegypti is the main vector for […]

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New study reveals an unexpected survival mechanism of a subset of cancer cells

Embedded at the ends of chromosomes are structures called telomeres, which in normal cells become shorter as cells divide. Progressive shortening triggers cell proliferation arrest or death. Cancer cells adopt different strategies to overcome this control mechanism that keeps track of the number of times that a cell has divided. One of these strategies is the alternative lengthening of telomeres […]

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New opioid speeds up recovery without increasing pain sensitivity or risk of chronic pain

Morphine and other opioid-based painkillers are very effective at treating pain initially, but studies have shown that the drugs can make patients more pain-sensitive, prolonging their discomfort and increasing their risks of developing chronic pain. A new type of opioid developed by researchers at Tulane University and the Southeast Louisiana Veterans Health Care System doesn’t have this side effect and […]

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Quieter intensive care units may translate to better outcomes for infants in new study

Excessive noise is widely known to have negative effects on health, and children in neonatal intensive care units are among the most vulnerable. To help preterm infants make a smooth transition to life outside of the womb, some NICUs have instituted set quiet times to limit children’s exposure to potentially dangerous levels of noise. Researchers from the University of Nebraska-Lincoln, […]

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Making the invisible visible: New method opens unexplored realms for liquid biopsies

Advancing technology is allowing scientists increasingly to search for tiny signs of cancer and other health issues in samples of patients’ blood and urine. These “liquid biopsies” are less invasive than a traditional biopsy, and can provide information about what’s happening throughout the body instead of just at a single site. Now researchers at the University of Michigan Rogel Cancer […]

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