New investigational antibiotic effective against drug-resistant bacteria in phase 2 trial

Results from a phase 2 randomised trial suggest that a new investigational antibiotic is as effective as the current standard-of-care antibiotic for the treatment of complicated urinary tract infections (UTIs) caused by several multidrug resistant Gram-negative bacteria. The findings, published in The Lancet Infectious Diseases, indicated that patients treated with the siderophore-based drug, cefiderocol, had a higher and more sustained […]

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What is the virus that has killed 7 children in New Jersey?

(HealthDay)—New Jersey health officials on Wednesday confirmed the deaths of seven children following infection with an adenovirus—a member of the same viral family that causes the common cold. Eleven other children are infected, and all cases occurred at the same health care facility, the Wanaque Center for Nursing and Rehabilitation in Haskell, according to N.J. Commissioner of Health Dr. Shereef […]

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New drug slashes death rates among drug-resistant TB patients: scientists

Credit: CC0 Public Domain A new treatment for a deadly drug-resistant strain of tuberculosis can cure more than 90 percent of sufferers, according to a landmark clinical trial whose results were revealed exclusively to AFP. Doctors in Belarus—a country with one of the world’s highest rates of multidrug-resistant tuberculosis—treated 181 patients with the new drug, bedaquiline, in combination with other […]

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New imaging tool captures how sound moves through the chinchilla ear

Researchers have developed a new device that can be used to visualize how sound-induced vibrations travel through the ear. The technology is providing new insight into how the ear receives and processes sound waves and, with additional development, might one day be used by physicians to diagnose diseases that affect hearing. The new imaging tool is based on optical coherence […]

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Study holds promise for new pediatric brain tumor treatment

New research published in Nature Communications from scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U), in collaboration with the Stanford University School of Medicine, shows a specific protein regulates both the initiation of cancer spreading and the self-renewal of cancer cells in medulloblastoma, a type of pediatric brain cancer. Among children’s cancers, brain cancer […]

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New approach could jumpstart breathing after spinal cord injury

A research team at the Krembil Research Institute in Toronto has developed an innovative strategy that could help to restore breathing following traumatic spinal cord injury. The team, led by principal investigator Dr. Michael Fehlings—a neurosurgeon/neuroscientist, specialist in spinal cord injury and senior scientist at UHN—published its findings today in the journal Nature in a paper titled “Cervical excitatory neurons […]

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New clues about how our body guards against cancer

Walter and Eliza Hall Institute researchers have uncovered a key factor protecting against age-related DNA damage, providing important clues about how our body guards against cancer. The discovery was made by identifying a rare genetic mutation in three patients with an unusual, early-onset form of acute myeloid leukaemia (AML). The patients all lacked a DNA repair protein called MBD4, which […]

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Brigatinib becomes potential new first-line option for ALK-positive non-small lung cancer

Results of a 275-patient, multi-national phase III clinical trial known as ALTA-1L published today in the New England Journal of Medicine and presented concurrently in the press program at the International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer 2018 argue for brigatinib as a first-line treatment option for advanced ALK-positive non-small cell lung cancer. […]

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