Study reveals long-term effectiveness of therapy for common cause of kidney failure

New research provides support for the long-term efficacy of a drug used to treat in patients with autosomal dominant polycystic kidney disease (ADPKD), a common cause of kidney failure. The findings appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The hormone vasopressin promotes the progression of ADPKD, the fourth leading cause of […]

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Study finds a novel and more practical way to measure kidney function

Researchers working on a study to improve kidney function measurements have found a way to provide more accurate readings. Using an injectable biomarker, physicians were able to read the actual working capacity of the kidney in a clinical setting in half the time it used to take. Currently, physicians rely on estimated kidney function (or estimated glomerular filtration rate) to […]

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Common diabetes drug found safe for most diabetics with kidney disease

Results of a large-scale study suggest that the oral diabetes drug metformin is safe for most diabetics who also have chronic kidney disease (CKD). The study of more than 150,000 adults by Johns Hopkins Medicine investigators found that metformin’s association with the development of a life-threatening condition called lactic acidosis was seen only among patients with severely decreased kidney function. […]

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Link between HPV and cancer after kidney transplant

The European Cancer Stem Cell Research Institute at Cardiff University has shed light on the link between skin cancer development and kidney transplants, highlighting the importance for clinicians to monitor transplant patients for these virus-induced cancers. In patients who lack the protection of their immune system, viruses like HPV can spread and cause cancer unchecked. This means that those receiving […]

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Women with pregnancy-related diabetes may be at risk for chronic kidney disease

Gestational diabetes may predispose women to early-stage kidney damage, a precursor to chronic kidney disease, according to a study by researchers at the National Institutes of Health and other institutions. The study appears in Diabetes Care. Gestational diabetes occurs only in pregnancy and results when the level of blood sugar is too high. The condition increases the risk for preterm […]

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‘Killer’ kidney cancers identified by studying their evolution

Scientists have discovered that kidney cancer follows distinct evolutionary paths, enabling them to detect whether a tumour will be aggressive and revealing that the first seeds of kidney cancer are sown as early as childhood. The three Cancer Research UK funded studies, published in the journal Cell, shed light on the fundamental principles of cancer evolution and could lead to […]

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Massive single-cell survey of kidney cell types reveals new paths to disease

The kidney is a highly complex organ – far beyond a simple filter. Its function requires intricate interactions between many highly specialized cell types to extract waste, balances body fluids, form urine, regulate blood pressure, and secrete hormones. New research from a team in the Perelman School of Medicine at the University of Pennsylvania shines a light on specific cell […]

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