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Possible new treatment for spinal cord injuries identified in animal studies

11.06.2018 Health Problems

An experimental drug has shown promise as a potential therapy for spinal cord injuries in animal studies. The compound, 4-aminopyridine-3-methanol, works in a similar way as a drug previously developed at Purdue, 4-aminopyridine (4-AP), which has been approved by the U.S. Food and Drug Administration to treat multiple sclerosis. Dr. Riyi Shi, professor in the Department of Basic Medical Sciences, […]

Newly identified genetic markers classify previously undetermined glioblastoma tumors

05.06.2018 Health Problems

Most glioblastoma tumors are marked by one or two broad mutation patterns, but about 20 percent of the lethal brain tumors have biomarkers that cannot be identified. Now scientists at Duke Cancer Institute have identified mutations for the vast majority of the remaining 20 percent of uncharacterized tumors, which tend to be especially lethal. The findings indicate that these mutations […]

Gene mutation linked to aggressive brain tumour identified

30.04.2018 Health Problems

Researchers at the Indian Institute of Science (IISc) have uncovered a previously unknown gene mutation that is linked to a highly aggressive form of a brain tumour called glioblastoma. This deadly tumour grows and spreads very quickly in the brain, and is difficult to treat. Even with available treatment, patients survive on average only for 15 to 17 months after […]

Novel pathway identified in development of acute myeloid leukemia with poor prognosis

25.04.2018 Health Problems

Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow that comprises 1 percent of all new cancer cases and almost 2 percent of cancer deaths in the U.S. The five-year survival rate for the disease is less than 20 percent. Researchers at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore […]

‘Killer’ kidney cancers identified by studying their evolution

12.04.2018 Health Problems

Scientists have discovered that kidney cancer follows distinct evolutionary paths, enabling them to detect whether a tumour will be aggressive and revealing that the first seeds of kidney cancer are sown as early as childhood. The three Cancer Research UK funded studies, published in the journal Cell, shed light on the fundamental principles of cancer evolution and could lead to […]

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