Novel regulator of mitochondrial cell death reveals a promising target for cancer therapy

Researchers at The Wistar Institute have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. They also found that expression of MFF is regulated by Myc, a ubiquitous mediator of cell proliferation that contributes to development of many cancer types. These results were published online in […]

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For gut microbes, not all types of fiber are created equal

Certain human gut microbes with links to health thrive when fed specific types of ingredients in dietary fibers, according to a new study from Washington University School of Medicine in St. Louis. The work—conducted in mice colonized with human gut bacteria and using new technologies for measuring nutrient processing—is a step toward developing more nutritious foods based on a strategy […]

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Researchers identify potential target for cardiac fibrosis treatment

A research team led by scientists from the Consortium for Fibrosis Research & Translation (CFReT) at the University of Colorado School of Medicine has identified a potential target for treating heart failure related to fibrosis. Fibrosis is a wound-healing response after tissue injury or stress. Cardiac fibrosis can cause abnormal stiffening of the heart, contributing to the pathogenesis of heart […]

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Headache from epidural for labor may up subdural hematoma risk

(HealthDay)—The presence of presumed postdural puncture headache after neuraxial anesthesia (epidural or spinal) in childbirth is associated with an increased risk for being diagnosed with an intracranial subdural hematoma, according to a study published online Sept. 16 in JAMA Neurology. Albert R. Moore, M.D., from McGill University in Montreal, and colleagues examined the correlation between postdural puncture headache and postpartum […]

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Scientists discover new breakthrough in treatment for cancer hair loss

Scientists have determined a new way to protect the hair follicle from chemotherapy in an effort to prevent hair loss as a result of cancer treatments. Researchers based at The University of Manchester have discovered a new strategy for how to protect hair follicles from chemotherapy, which could lead to new treatments that prevent chemotherapy-induced hair loss—arguably one of the […]

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Scientists isolate protective proteins that influence outcomes for type 2 diabetes

Scientists from the School of Medicine, Trinity College Dublin, have, for the first time, discovered a family of proteins that are associated with lower blood sugar levels among obese patients with type 2 diabetes. Their research is published today in the international journal Nature Communications. The study showed that patients with type 2 diabetes who have high levels of the […]

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