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The right mouse model is crucial for Huntington’s disease drug development

11.12.2019 Health Problems

Huntington’s disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies. Their findings are published in the Journal of […]

Eating only during a 10-hour window improved health for those with metabolic syndrome

05.12.2019 Health Problems

What if a clock did a better job than a scale at promoting weight loss, improving sleep and preventing diabetes? New research suggests it’s about time to consider that possibility. In an early effort to explore the benefits of daily fasting in humans, researchers have found that people who are at high risk of developing diabetes improved their health in […]

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

04.12.2019 Health Problems

Kidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression with an experimental drug called tivozanib compared to an alternative approved by the U.S. Food and Drug Administration, according to a City of Hope-led study. “This agent has shown in clinical trials to be effective in delaying cancer growth beyond established […]

The Best Dolls for Boys in 2020 — & Why They Matter So Much

03.12.2019 Kids Health

It might be news to toy stores that still (still!) label their aisles “boys toys” and “girls toys” (or grandparents who insist your daughter would really like a miniature vacuum cleaner for her birthday while your son needs a train set), but guess what: Kids don’t care about gender stereotypes. And if they do, it’s because we have conditioned them […]

Computer simulations help develop medical treatment for skin conditions

29.11.2019 Health Problems

Computer simulations created by researchers at the University of St Andrews could be used to create more effective treatments for tackling medical issues such as skin conditions. Research carried out at the University of St Andrews used algorithms usually used in astronomy to test how certain treatments would work in medical trials. The research team used the algorithms to assess […]

Trials promise good news for countries with dengue and Zika virus

21.11.2019 Health Problems

An international team of scientists have reported an effective and environmentally sustainable way to block the transmission of mosquito-borne dengue virus, in trials carried out in Malaysia. The breakthrough has major implications for countries with hot climates such as island nations in the South Pacific to Saudi Arabia, Africa and South America, all of which experience dengue, Zika, yellow fever […]

The high cost challenge of personalised screening for bowel cancer

21.11.2019 Health Problems

Personalised screening could improve the diagnosis of bowel cancer and re-shape the future of Australia’s National Bowel Cancer Screening Program (NBCSP), according to new research at The University of Western Australia. The study, published today in Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research, hopes to improve health outcomes by targeting screening at those […]

Wearable and implantable devices may transform care for patients with kidney failure

15.11.2019 Health Problems

A feature article appearing in an upcoming issue of CJASN highlights the potential of wearable and implantable devices for treating kidney failure. In their feature article, Shuvo Roy, Ph.D. (University of California, San Francisco) and his colleagues note that traditional hemodialysis performed in clinics has a number of shortcomings, with patients reporting burdens related to fatigue, poor sleep, inability to […]

Study: Multidisciplinary transplantation evaluation shows promise for older adults

14.11.2019 Health Problems

Older adults with blood cancers can benefit from a team-based, holistic evaluation before undergoing transplantation, according to a new study published today in Blood Advances. The study, which reported on a multidisciplinary clinic (MDC) at the University of Chicago Medical Center, found that patients treated with this approach experienced better transplantation outcomes and survival rates. Most blood cancers that can […]

Chemotherapy sometimes set the stage for drug-resistant leukemia at relapse

02.11.2019 Health Problems

Chemotherapy has helped make the most common childhood cancer one of the most curable, but researchers have evidence that the treatment may also prime some patients for relapse. Results published in the journal Blood reported that treatment-induced mutations cause drug resistance in some patients whose acute lymphoblastic leukemia (ALL) returns. “Our study reveals the evolution dynamics of pediatric ALL, which […]

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