Strategies for working through daily stress

Stress affects most Americans at one point or another. Although some people are genetically more susceptible to the stressors of daily life than others, most could benefit from learning how to lower that stress before it negatively affects their physical and mental health. Julie Radico, a psychologist and behavioral scientist at Penn State Health Milton S. Hershey Medical Center, said […]

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Newly identified drug target in rheumatoid arthritis paves way for development of new therapies

University of Melbourne researchers have identified a protein involved in rheumatoid arthritis-induced inflammation that could lead to new drug treatments for people who do not respond to current therapies. Arthritis is Australia’s most common chronic disease and affects more than 3.5 million people. Rheumatoid arthritis (RA) affects about one per cent of the population and is one of the most […]

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Interim guidance provided for men with possible Zika infection

(HealthDay)—Interim guidance recommends that men with possible Zika virus infection wait three months before trying to conceive or engaging in unprotected sex, according to research published in the Aug. 10 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report. Kara D. Polen, M.P.H., from the CDC in Atlanta, and colleagues updated interim guidance for […]

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New compound advances into Phase 1 trial for pancreatic cancer

A compound discovered at Sanford Burnham Prebys Medical Discovery Institute (SBP) has advanced into a Phase 1 trial for metastatic pancreatic cancer. Called CEND-1 (scientifically known as iRGD), the compound was exclusively licensed in 2015 to a private company, DrugCendR Inc. The drug candidate was discovered in the laboratory of Erkki Ruoslahti, M.D., Ph.D., distinguished professor at SBP and founder, […]

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Thrombospondin-1 may serve as a potential therapeutic target for thoracic aortic aneurysms

Researchers at the University of Tsukuba and Kansai Medical University in Japan reveal matricellular protein Thrombospondin-1 (Thbs1) contributes to the development of aortic aneurysm in mice and humans. The thoracic aorta is constantly exposed to mechanical forces generated by heart contraction and blood flow. Thoracic aortic aneurysms (TAAs) are life-threatening diseases defined as a permanent abnormal dilatation of the thoracic […]

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Risk factors for faulty rhythms

Arrhythmias—disruptions in the rhythm of the heartbeat—after congenital heart disease (CHD) surgery in children are common and contribute to increased morbidity and mortality. Prince Kannankeril, MD, MSCI, and colleagues explored clinical and genetic factors associated with atrial tachycardia (AT) after CHD surgery in infants younger than 1 year old. They examined variants in the genes PITX2 and IL6, which are […]

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For children with complex medical situations, a new roadmap for improving health

Children with severe disabilities, serious cognitive impairments and medically complex situations require more specialized health care during their lifetimes. But establishing a consistent way to identify their overall health needs and measure progress in meeting those needs has been an elusive goal. A team of UCLA researchers has developed a set of health outcome measures for such children using a […]

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Best Matching Outfits for Twins

If you’re a parent of twins, chances are you’ve had the inclination at some point to dress that dynamic duo up in matching or coordinating outfits — whether for family holiday card photos or to keep an easy eye on the kids while traveling or out shopping. But personally, I worried that my boy-girl twins would one day look back […]

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Intervention cuts risk for HIV in young transgender women

(HealthDay)—A culturally specific, empowerment-based, and group-delivered behavioral prevention intervention can reduce sexual risk for HIV acquisition and transmission in sexually active young transgender women (YTW), according to a study published online Aug. 13 in JAMA Pediatrics. Robert Garofalo, M.D., M.P.H., from the Ann & Robert H. Lurie Children’s Hospital in Chicago, and colleagues conducted a randomized efficacy trial of a […]

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