diseases Archives - Family Medicine News

Consortium to investigate role of neurofilament light chain in neurodegenerative diseases

13.04.2021 Health Problems

Clinical scientists at Washington University School of Medicine in St. Louis and University College London are collaborating with pharmaceutical companies AbbVie, Biogen, Bristol Myers Squibb and Roche to investigate the role of neurofilament light (NfL) chain in neurodegenerative diseases such as amyotrophic lateral sclerosis, Parkinson’s disease, Huntington’s disease and Alzheimer’s disease. NfL is a protein that provides structural support to […]

Inflammatory processes drive progression of Alzheimer’s and other brain diseases

20.11.2019 Health Problems

Inflammation drives the progression of neurodegenerative brain diseases and plays a major role in the accumulation of tau proteins within neurons. An international research team led by the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn comes to this conclusion in the journal Nature. The findings are based on the analyses of human brain tissue and further […]

Using math to help treat Alzheimer’s, Parkinson’s and other diseases

16.08.2019 Health Problems

Protein aggregation—in which misfolded proteins clump together to form large fibrils—has been implicated in many diseases including Alzheimer’s, Parkinson’s, and type II diabetes. While the exact role these fibrils play in diseases isn’t fully understood, many of the current treatments for diseases like Alzheimer’s and Parkinson’s target the aggregation process. However, finding the right treatment protocols for these drugs, which […]

Study: Racial tension may stem from fear of exposure to infectious diseases

06.08.2019 Health Problems

Social scientists have long worked to understand the roots of racial prejudice in the U.S., and for years, the story went like this: As different groups are exposed to others, their prejudice against those others increases. Brian O’Shea wasn’t buying it. A postdoctoral fellow working in the lab of Matt Nock, the Edgar Pierce Professor of Psychology, O’Shea is the […]

Bacteria-mimicking particles may help treat infectious diseases

25.03.2019 Health Problems

Unique particles modified to mimic bacteria may provide a better means of treating infectious diseases, such as tuberculosis. Assistant Professor Joshua Reineke of the South Dakota State University Department of Pharmaceutical Sciences and his team modified microparticles, known as metal organic frameworks (MOFs), developed by a research group in France. Other researchers have explored MOFs as a drug-delivery system to […]

Scientists search for new methods to cure neurodegenerative diseases

18.01.2019 Health Problems

Most neurons in the human brain are generated from neural stem cells during embryonic development. After birth, a small reservoir of stem cells remain in the brain that keeps on producing new neurons throughout life. However, the question arises as to whether these new neurons really support brain function? And if so, can we improve brain capacity by increasing the […]

FDA approves drugs for treatment of two rare blood diseases

25.12.2018 Health Problems

(HealthDay)—Two drugs have been approved by the U.S. Food and Drug Administration for the treatment of rare blood diseases, the agency announced Friday. Elzonris (tagraxofusp-erzs) infusion was granted the first approval for the treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN) in adults and children aged 2 years and older. Researchers investigated the efficacy of Elzonris in two patient cohorts […]

Ground-breaking discovery finds new link between autoimmune diseases and a gut bacterium

29.10.2018 Health Problems

Could microbes in our guts be sending out the wrong message? Queen’s University Belfast researchers have, for the first time, found a specific microbe in the gut that pumps out protein molecules that mimic a human protein, causing the human defence system to turn on its own cells by mistake. The culprit in this case is called Bacteroides fragilis, a […]

How astrophysics could transform the treatment of cystic fibrosis and other rare diseases

05.10.2018 Health Problems

It’s a cruel disease which dramatically shortens life expectancy. One in 25 Europeans carry the cystic fibrosis gene and, in the UK, about 10,400 people currently have the condition. But people are living longer and longer thanks to improvements in screening at birth, early treatment and medication. One of the most important things is for patients to be put on […]

Study finds that enzymes ‘partner up’ to accelerate cancer, aging diseases

26.09.2018 Health Problems

A new study from molecular biologists at Indiana University has identified cellular processes that appear to supercharge both the growth and shrinkage of the chemical “caps” on chromosomes associated with aging, called telomeres. The work, focused on two enzymes in yeast, could lead to new insights on stopping runaway cellular growth in cancer tumors, as well as the treatment of […]

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