Breaking the dogma: Key cell death regulator has more than one way to get the job done

Scientists at St. Jude Children’s Research Hospital have discovered a new way that the molecule RIPK1 leads to cell death in infected, damaged or unwanted cells showing that more than one mechanism can trigger the process. The findings appeared online today in the Journal of Experimental Medicine. “Our findings break the existing dogma that RIPK1 kinase activity is required for […]

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Artificial intelligence can now predict long-term risks of heart attack and cardiac death

A new study in Cardiovascular Research finds that machine learning, the patterns and inferences computers use to learn to perform tasks, can predict the long-term risk of heart attack and cardiac death. Indeed, machine learning appears to be better at predicting heart attacks and cardiac deaths than the standard clinical risk assessment used by cardiologists. Researchers here studied subjects from […]

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Study examines causes of death in US breast cancer survivors

Survival rates for patients with breast cancer have improved significantly in the last four decades, and many patients will eventually die from non-cancer-related causes. Researchers recently conducted the largest population-based long-term retrospective analysis of non-cancer causes of death among patients with breast cancer. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society. Of […]

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First donation after circulatory death heart transplant performed in the U.S.

A team of doctors at Duke University has carried out the first donation after circulatory (or cardiac) death (DCD) heart transplant in the U.S. Members of the surgical team have spoken with the press giving some details of the procedure. Over the past several decades, heart transplants have become routine—saving the lives of thousands of people. But in recent years, […]

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Miguel Cervantes' Wife Reveals the Sentimental Tattoo She Got on Their Late Daughter's Birthday

Miguel Cervantes‘ wife got a very special tattoo on what would have been their daughter Adelaide‘s fourth birthday. “Last week, on Miss Adelaide’s birthday, my mom and I did a thing,” Kelly Cervantes wrote Thursday on Instagram alongside a slideshow of images from their trip to get matching ladybug tattoos — a nod to Adelaide, who was nicknamed Adelaidey Bug. […]

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Novel regulator of mitochondrial cell death reveals a promising target for cancer therapy

Researchers at The Wistar Institute have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target. They also found that expression of MFF is regulated by Myc, a ubiquitous mediator of cell proliferation that contributes to development of many cancer types. These results were published online in […]

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