Reducing cholesterol could enhance T-cell cancer immunotherapy

Cleveland Clinic researchers have demonstrated for the first time that lowering blood cholesterol levels could enhance the success of a specific type of T-cell immunotherapy in fighting cancer. The team, led by Qing Yi, MD, Ph.D., of Cleveland Clinic Lerner Research Institute studied T-cell transfer, which has shown great success in recent years. Dr. Yi previously showed that a specific […]

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Understanding veteran privacy rules could help improve counseling strategies

When combat veterans return home, they often are faced with questions about what they experienced overseas. However, choosing to disclose this information can be complicated, as responses can impact one’s public image and personal relationships. Now, a researcher at the University of Missouri has found that veterans tend to disclose wartime information on a strict need-to-know basis, and that therapists […]

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Reduction in federal funding could reduce quality of specialized pediatric care

Hospitals caring for children with serious, chronic illness are highly dependent on public payers, according to a new study. The research found that proposals to dramatically reduce federal expenditures on Medicaid and Children’s Health Insurance Program (CHIP) could destabilize current specialty care referral networks serving all children, including the majority of privately-insured children in greatest need of high quality, specialized, […]

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New tools could uncover important answers for Alzheimer’s researchers

Alzheimer’s disease currently affects more than 5.5 million Americans and is one of the costliest diseases to treat, according to the Alzheimer’s Association. Characterized by a buildup of plaque in the brain, few animal models exist that researchers could use to study this devastating disorder. Now, a team of researchers from the University of Missouri, publishing in PLOS ONE, developed […]

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Infections could trigger stroke in pregnant women during hospital delivery

Pregnant women who have an infection when they enter the hospital for delivery might be at higher risk of having a stroke during their stay, according to new research. The study, published Friday in the journal Stroke, tried to determine if infections contribute to stroke risk during peripartum, a term meaning shortly before or after childbirth. While maternal strokes are […]

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Eyes of adolescents could reveal risk of cardiovascular disease

New research has found that poorer well-being or ‘health-related quality of life’ (HRQoL) in adolescence could be an indicator of future cardiovascular disease risk. Researchers at The Westmead Institute for Medical Research found that adolescents with poorer scores in the social and mental well-being domains of HRQoL have structural changes in their retinal blood vessels that could be associated with […]

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Sunshine could hold clues on the timing for a severe form of heart attack, study says

The sun’s radiation could be a factor in seasonal patterns of a deadly type of heart attack, according to new research that tracked a “summer shift” in their occurrence across seven countries. Previous research has examined how these attacks – called ST-elevation myocardial infarctions, or STEMIs – seem to happen most often in the daytime during the colder winter months, […]

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