Treating Breast Cancer Using Antibiotics

Skip to: A Toxin Capable of Halting a Signaling Pathway Achieving Tumour Growth Inhibition The Promise of Drug Repurposing in the Future Triple-negative breast cancer (TNBC) describes the form of the disease that lacks the expression of 3 receptors: estrogen, progesterone, and HER2. Up to 15% of breast cancers are considered to be TNBC, which is correlated with an elevated […]

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What I Gained When My Hair Fell Out

For people who‘ve undergone treatments for cancer, hair loss is a common but nevertheless stressful side effect. And, contrary to popular belief, the hard part isn’t over when your hair starts to return. Here, survivor Sarah Ochoa shares what she learned about herself during her post-treatment hair journey. This story is part of our series on women's experiences with cancer […]

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Chemotherapy sometimes set the stage for drug-resistant leukemia at relapse

Chemotherapy has helped make the most common childhood cancer one of the most curable, but researchers have evidence that the treatment may also prime some patients for relapse. Results published in the journal Blood reported that treatment-induced mutations cause drug resistance in some patients whose acute lymphoblastic leukemia (ALL) returns. “Our study reveals the evolution dynamics of pediatric ALL, which […]

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Mouse study mirrors human findings that link chemotherapy and APOE4 to cognitive issues

The research, led by Georgetown University Medical Center (GUMC) investigators and published in Neurotoxicity Research, complements findings from another GUMC-led study, published Oct. 3, that found a subset of breast cancer patients who experience long lasting cognitive deficits also have the APOE4 gene. Cancer survivors often report memory difficulties and this study, published in the Journal of Clinical Oncology (JCO), […]

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New treatment helps avoid deafness in child chemotherapy patients

An international trial has found that a medicine commonly used to treat poisoning is effective in reducing deafness in children receiving chemotherapy for cancer. University of Melbourne and Royal Children’s Hospital paediatric oncologist Professor Michael Sullivan was international vice chair of the study, results of which are published in today’s New England Journal of Medicine. Professor Sullivan said the trial […]

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TAILORx trial finds most women with early breast cancer do not benefit from chemotherapy

New findings from the groundbreaking Trial Assigning Individualized Options for Treatment (Rx), or TAILORx trial, show no benefit from chemotherapy for 70 percent of women with the most common type of breast cancer. The study found that for women with hormone receptor (HR)-positive, HER2-negative, axillary lymph node¬-negative breast cancer, treatment with chemotherapy and hormone therapy after surgery is not more […]

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Trial shows chemotherapy is helping kids live with pulmonary vein stenosis

Pulmonary vein stenosis (PVS) is a rare disease in which abnormal cells build up inside the veins responsible for carrying oxygen-rich blood from the lungs to the heart. It restricts blood flow through these vessels, eventually sealing them off entirely if left untreated. Typically affecting young children, the most severe form of PVS progresses very quickly and can cause death […]

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Using mathematical models to determine the best chemotherapy schedules

Can mathematical models predict how can cancer cells respond to varied chemotherapy schedules? In other words, should cancers associated with fast-growing tumors, like brain cancer, be treated using a low drug dose administered continuously, as opposed to a high drug dose given periodically? Professor Paul Newton and Ph.D. recipient Jeffrey West have developed a tool that can predict the best […]

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