T cell biomarker predicts which CLL patients will respond to CAR T cell therapy

Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia (CLL) don’t respond to chimeric antigen receptor (CAR) T cell therapy, and the answer is tied to how primed patients’ immune systems are before the therapy is administered. While 80 percent of patients with advanced acute lymphoblastic leukemia (ALL) treated with the CAR T […]

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Studies show promise of immunotherapy combinations, including CAR T

As immunotherapies continue to make up a larger share of new cancer drugs, researchers are looking for the most effective ways to use these cutting edge treatments in combination with each or with other pre-existing options. New studies from the Abramson Cancer Center of the University of Pennsylvania are providing fresh clues on potentially effective combinations with CAR T therapy […]

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Study explores safety of rear-facing car seats in rear impact car crashes

Rear-facing car seats have been shown to significantly reduce infant and toddler fatalities and injuries in frontal and side-impact crashes, but they’re rarely discussed in terms of rear-impact collisions. Because rear-impact crashes account for more than 25 percent of all accidents, researchers at The Ohio State University Wexner Medical Center conducted a new study to explore the effectiveness of rear-facing […]

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