familymednews.com
With CAR T cell therapy, a patient’s own immune cells are genetically modified and inserted back into the body to find and kill cancer. This form of immunotherapy has already revolutionized some cancer treatments, but once the CAR T cells are inside a patient, where do they go? How do doctors know that they have successfully reached their target and […]
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Ah, the car: Part form of personal transportation, part dumping ground for the detritus that gets left behind as we travel from point A to point B. If your family car looks like something out of an archeological dig, you’re not alone. (“Ah, yes, the fossilized Cheerio, a primary source of nourishment for the American child at the dawn of […]
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If you’re a parent, you’ve probably let your little one sleep in their car seat. It is easy and convenient, plus most of us don’t give it a second thought. I mean, your baby is strapped in and safe, right? Well, think again. According to a new study, babies should not stay asleep in their car seat when they’re not […]
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An advance in the breakthrough cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, a new USC study shows. “This is a major improvement,” said Si-Yi Chen of the USC Norris Comprehensive Cancer Center, professor in the Department of Molecular Microbiology and Immunology at the […]
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CAR T-cell therapy, which reprograms immune cells to fight cancer, has shown great promise in people with some blood cancers who have not responded to other treatments. But until now, the underlying biological pathways enabling anti-cancer responses have not been thoroughly examined. Understanding these pathways is important for designing future generations of CAR T-cell therapies, including reducing side effects, preventing […]
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A lot of things change when you become a parent: your sleep schedule, your after-work priorities, the food in your fridge. Another change? Whether you can just jump in a car. The days of grabbing your purse and going are on hiatus. In their place is a complicated system of making sure you have everything you and your kids need […]
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(HealthDay)—Before the summer of 2018 was even one day old, 16 American kids had died after being left in hot cars, according to a group called KidsAndCars.org. Last year’s toll was 43, and, on average, 37 children die in hot cars each year in the United States. “We know there are families all across America right now holding their precious […]
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The doctors who have spent years studying the case call it “a series of fortunate events.” What began as a remarkable response to chimeric antigen receptor (CAR) T cell therapy is now providing evidence about the human genome and immune response that could help turn gene therapy non-responders into responders. Researchers at the University of Pennsylvania’s Abramson Cancer Center say […]
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Two teams of researchers, one working in the U.S., the other in Italy, have come up with new ways to avert cytokine release syndrome (CRS) in leukemia patients who undergo CAR T-cell therapies. In the first, the researchers working at the Sloan Kettering Cancer Center in New York developed a mouse model to replicate the conditions under which CRS develops. […]
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The U.S. Food and Drug Administration (FDA) has expanded approval for a personalized cellular therapy developed at the University of Pennsylvania’s Abramson Cancer Center, this time for the treatment of adult patients with relapsed or refractory large B-Cell lymphoma after two or more lines of systemic therapy. Today’s approval includes treatment of diffuse large B-cell lymphoma (DLBCL) – the most […]
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