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People diagnosed with the aggressive brain cancer glioblastoma face a grim prognosis. Half die within 14 months of diagnosis. Even if initial treatment with surgery, radiation and chemotherapy is successful, such brain tumors typically recur, leaving patients with few options. Now, a research team at Washington University School of Medicine in St. Louis has found that laser treatment designed to […]
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A technique using live human cancer tissue to develop the next generation of cancer drugs is being developed in South Australia. The researchers from the University of Adelaide are using the technique to fill the void between animal testing and clinical trials in a bid to cut the cost and time of drug development and reduce the failure rate in […]
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A compound discovered at Sanford Burnham Prebys Medical Discovery Institute (SBP) has advanced into a Phase 1 trial for metastatic pancreatic cancer. Called CEND-1 (scientifically known as iRGD), the compound was exclusively licensed in 2015 to a private company, DrugCendR Inc. The drug candidate was discovered in the laboratory of Erkki Ruoslahti, M.D., Ph.D., distinguished professor at SBP and founder, […]
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A new study provides insights into the degree to which socioeconomic status explains racial and ethnic disparities in childhood cancer survival. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the findings may inform where to allocate resources to best reduce racial and ethnic survival disparities for each of the major types of childhood cancer. For […]
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(HealthDay)—Most women with postmenopausal bleeding (PMB) will not be diagnosed with endometrial cancer, according to a review published online Aug. 6 in JAMA Internal Medicine. Megan A. Clarke, Ph.D., from the National Cancer Institute in Rockville, Md., and colleagues conducted a systematic literature review and meta-analysis to provide a reference of the prevalence of PMB in endometrial cancers and the […]
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Chemicals produced by vegetables such as kale, cabbage and broccoli could help to maintain a healthy gut and prevent colon cancer, a new study from the Francis Crick Institute shows. The research, published in Immunity, shows that mice fed on a diet rich in indole-3-carbinol—which is produced when we digest vegetables from the Brassica genus—were protected from gut inflammation and […]
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Lymphatic vessels actively contribute to the spread of cancer metastases from various organs. This unexpected realisation is the result of a joint study by researchers from ETH Zurich and the University Hospital Zurich as part of the research initiative Skintegrity. Together with medical experts from the University Hospital Zurich, researchers from ETH Zurich have discovered a new mechanism by which […]
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Although national guidelines advise doctors to discuss the benefits and harms of lung cancer screening with high-risk patients because of a high rate of false positives and other factors, those conversations aren’t happening the way they should be, according to a study by researchers from the University of North Carolina Lineberger Comprehensive Cancer Center. Lung cancer screening is recommended for […]
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Although immunotherapy is seen as a very promising treatment for cancer, currently only 20 to 30 percent of patients respond positively. Being able to identify the people most likely to benefit from the costly therapy is a Holy Grail for oncologists. In the current online edition of JAMA Oncology, scientists at Wake Forest Baptist Medical Center report finding a new […]
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A research team led by Fergus Couch, Ph.D., a geneticist at Mayo Clinic, has identified specific genes associated with an increased risk for developing triple-negative breast cancer. Their research was published in the Journal of the National Cancer Institute. “Triple-negative breast cancer is an aggressive type of cancer that cannot be treated using targeted therapies,” says Dr. Couch. “It accounts […]
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