A cell atlas of the aging lung

Aging promotes lung function decline and increases susceptibility to diseases of the respiratory tract. In order to understand these effects in detail, researchers at Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL), analyzed the aging process in the lung at single-cell level using AI approaches. They have now presented this Atlas of the Aging Lung […]

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Study finds that enzymes ‘partner up’ to accelerate cancer, aging diseases

A new study from molecular biologists at Indiana University has identified cellular processes that appear to supercharge both the growth and shrinkage of the chemical “caps” on chromosomes associated with aging, called telomeres. The work, focused on two enzymes in yeast, could lead to new insights on stopping runaway cellular growth in cancer tumors, as well as the treatment of […]

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Research shows it’s possible to reverse damage caused by aging cells

What’s the secret to aging well? University of Minnesota Medical School researchers have answered it- on a cellular level. Aging starts in our cells, and those aging cells can hasten cellular senescence, leading to tissue dysfunction and related health impacts. New research involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer, recently published in Nature […]

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Mouse study identifies new target for human accelerated aging syndrome

Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterised by premature ageing. In a paper published today in Nature Communications, scientists provide preclinical data showing that chemical inhibition or genetic deregulation of the enzyme N-acetyltransferase 10 (NAT10) leads to significant health and lifespan gains in […]

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