Selection of a pyrethroid metabolic enzyme CYP9K1 by malaria control activities

Researchers from LSTM, with partners from a number of international institutions, have shown the rapid selection of a novel P450 enzyme leading to insecticide resistance in a major malaria vector. In a paper published in PNAS the team of researchers led by LSTM’s Professor Janet Hemingway describe how operational malaria control activities, and a move back to pyrethroid based indoor […]

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Pharmacist follow-ups cut diabetes costs and reduce health risks

Two studies led by Associate Professor Joyce Lee from the Department of Pharmacy at the National University of Singapore’s (NUS) Faculty of Science revealed that pharmacist-managed care, in addition to routine check-ups with physicians, help improve the management of diabetes and the associated chronic diseases. NUS researchers found that people with type 2 diabetes who regularly saw Ambulatory Care pharmacists […]

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Research finds new mechanism that can cause the spread of deadly infection

Scientists at the University of Birmingham have discovered a unique mechanism that drives the spread of a deadly infection. Cptococcosirys is a rare and deadly fungal infection that affects the lung and brain and usually only occurs in people with impaired immunity. However, one strain of the fungus – known as the Pacific Northwest strain of Cryptococcus gattii – has […]

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Infections could trigger stroke in pregnant women during hospital delivery

Pregnant women who have an infection when they enter the hospital for delivery might be at higher risk of having a stroke during their stay, according to new research. The study, published Friday in the journal Stroke, tried to determine if infections contribute to stroke risk during peripartum, a term meaning shortly before or after childbirth. While maternal strokes are […]

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Can a brain injury change who you are?

Who we are, and what makes us “us” has been the topic of much debate throughout history. At the individual level, the ingredients for the unique essence of a person consist mostly of personality concepts. Things like kindness, warmth, hostility and selfishness. Deeper than this, however, is how we react to the world around us, respond socially, our moral reasoning, […]

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Compound improves stroke outcome by reducing lingering inflammation

An experimental compound appears to improve stroke outcome by reducing the destructive inflammation that can continue months after a stroke, scientists report. Rats consuming compound 21 following a clot-based stroke – the most common type in humans – don’t have a smaller stroke size but do have better memory and movement in its aftermath, says Dr. Adviye Ergul, vascular physiologist […]

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Novel antioxidant makes old blood vessels seem young again

Older adults who take a novel antioxidant that specifically targets cellular powerhouses, or mitochondria, see age-related vascular changes reverse by the equivalent of 15 to 20 years within six weeks, according to new University of Colorado Boulder research. The study, published this week in the American Heart Association journal Hypertension, adds to a growing body of evidence suggesting pharmaceutical-grade nutritional […]

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Protein can slow intestinal tumor growth

A new mechanism for regulating stem cells in the intestine of fruit flies has been discovered by researchers at Stockholm University. In addition, it was discovered that a certain protein can slow the growth of tumours in intestinal tissue. A better understanding of these mechanisms can teach us more about how diseases in human intestines occur, as well as contribute […]

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Molecule that dilates blood vessels hints at new way to treat heart disease

Americans die of heart or cardiovascular disease at an alarming rate. In fact, heart attacks, strokes and related diseases will kill an estimated 610,000 Americans this year alone. Some medications help, but to better tackle this problem, researchers need to know exactly how the heart and blood vessels stay healthy in the first place. Now, scientists at The Scripps Research […]

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Eyes of adolescents could reveal risk of cardiovascular disease

New research has found that poorer well-being or ‘health-related quality of life’ (HRQoL) in adolescence could be an indicator of future cardiovascular disease risk. Researchers at The Westmead Institute for Medical Research found that adolescents with poorer scores in the social and mental well-being domains of HRQoL have structural changes in their retinal blood vessels that could be associated with […]

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