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Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia (CLL) don’t respond to chimeric antigen receptor (CAR) T cell therapy, and the answer is tied to how primed patients’ immune systems are before the therapy is administered. While 80 percent of patients with advanced acute lymphoblastic leukemia (ALL) treated with the CAR T […]
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As many as one in three women treated for breast cancer undergo unnecessary procedures, but a new method for diagnosing it could do a better job distinguishing between benign and aggressive tumors. Researchers at the University of Michigan are developing a pill that makes tumors light up when exposed to infrared light, and they have demonstrated that the concept works […]
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3-D printing is an emerging technology that is impacting the way cardiologists treat patients with congenital heart disease (CHD), according to a review paper published today in JACC: Basic to Translational Science. The prevalence of CHD is approximately nine per 1,000 live births, and overall survival rates have steadily increased for even the most complex diseases; however, these patients face […]
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The tobacco industry manipulated the renowned children’s rights agency UNICEF for more than a dozen years, from 2003 until at least 2016, during which time UNICEF’s focus on children’s rights to a tobacco-free life was reduced, according to previously secret documents uncovered by UC San Francisco. The research appears April 30, 2018, in Pediatrics, the journal of the American Academy […]
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Researchers at the Indian Institute of Science (IISc) have uncovered a previously unknown gene mutation that is linked to a highly aggressive form of a brain tumour called glioblastoma. This deadly tumour grows and spreads very quickly in the brain, and is difficult to treat. Even with available treatment, patients survive on average only for 15 to 17 months after […]
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How would you describe an average teenager? For most people, the following characteristics might come to mind: moody, impulsive, risk taking, likely to succumb to peer pressure. While it’s clear that adolescence is a period of life that is rife with stereotypes, there is some truth to the cliches. Many neuroscience studies have now established that there are significant changes […]
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Anyone who has raised children or grown up with siblings knows there are some bumpy times in a child’s life. When the smallest upset causes a major tantrum. Or when it’s close to impossible to get them out the door on time for school. Or when your adorable angel acts like a wild animal. But some children’s tantrums, irritability and […]
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To a certain degree, everyone experiences stress: We feel nervous meeting with a job interviewer, have anxiety about making it to an appointment on time or feel ourselves holding our breath while watching a tense playoff game. These are normal, everyday stressors. But many people suffer from more severe or long-term stress, which can have damaging effects on our mind, […]
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In a study of adults with rheumatoid arthritis, those who were severely obese experienced more rapidly progressing disability than patients who were overweight. This was not explained by features of their arthritis, including the amount of inflammation in their joints. In the Arthritis Care & Research study, weight loss after enrollment was also associated with worsening disability, possibly as a […]
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(HealthDay)—If she’s fit, a woman is less likely to develop diabetes during pregnancy, a new study contends. Researchers who followed 1,300 U.S. women found that high levels of fitness before pregnancy were tied to a 21 percent lower risk of gestational diabetes. These findings show that women should think about getting into shape before conceiving, according to the University of […]
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