Breast tissue tumor suppressor PTEN: A potential Achilles heel for breast cancer cells

In an article published July 17, 2018 by Nature Communications, a highly collaborative team of researchers at the Medical University of South Carolina (MUSC) and Ohio State University report that normal breast cells can prevent successful radiation treatment of breast cancer due to dysregulation between tumor suppressors and oncogenes. Tumor suppressors act like brakes that stop cells from undergoing uncontrolled […]

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buprenorphine

PHOENIX, July 27, 2018 (GLOBE NEWSWIRE) — INSYS Therapeutics, Inc. (NASDAQ: INSY) announced that today it received a Complete Response Letter (CRL) from the U.S. Food and Drug Administration (FDA) regarding the company’s New Drug Application (NDA) for a buprenorphine sublingual spray as a treatment for moderate-to-severe acute pain. Consistent with the outcome of an FDA Advisory Committee meeting in […]

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Acupuncture may cut arthralgia from aromatase inhibitors

(HealthDay)—Acupuncture may cut joint pain among postmenopausal women with early-stage breast cancer and aromatase inhibitor-related pain, according to a study published in the July 10 issue of the Journal of the American Medical Association. Dawn L. Hershman, M.D., from Columbia University in New York City, and colleagues evaluated acupuncture for reducing aromatase inhibitor-related joint pain among postmenopausal women with early-stage […]

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Sharing your #shopping on social media can damage your health and your wallet

Posting images on social media when we buy new clothes, eat out or purchase the latest gadget may seem harmless enough. But this consumption-oriented sharing may be undermining both our bank balance and our mental well-being. Our research has found that this sort of social media engagement is linked in some people to greater anxiety, lower self-esteem and an increased […]

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Liver cancer cell ‘switch’ found that could improve future therapies

Imperial researchers have found a new cell mechanism that could be used to target tumours in the future. The newly discovered ‘switch’ controls the activity of two proteins – ‘deleted in liver cancer-1’ (DLC1), a tumour suppressor, and talin. Both proteins control whether or not cancer cells spread to other parts of the body, but the exact mechanisms have remained […]

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Kidstrology: Your Parenting Horoscope for August

The final full month of summer has arrived, and August is the last month dominated by the backward motion most of our planets are currently taking according to astrologer Scarlett McNamara.  "It’s a good time to reevaluate the things that are important," McNamara tells SheKnows, noting that we should focus on living in the moment this month. "Our energy and […]

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Fewer dialysis patients facing leg amputations

(HealthDay)—Losing a leg is one of the most traumatic consequences of advanced kidney disease, but the risk of amputations has dropped significantly since 2000, a new study finds. Between 2000 and 2014, amputations among U.S. patients with end-stage kidney disease who were receiving dialysis were cut by 51 percent. Despite the decrease, however, almost half of patients who had amputations […]

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Lack of a single molecule may indicate severe and treatment-resistant depression

People with depression have low blood levels of a substance called acetyl-L-carnitine, according to a Stanford University School of Medicine scientist and her collaborators in a multicenter study. Naturally produced in the body, acetyl-L-carnitine is also widely available in drugstores, supermarkets and health food catalogs as a nutritional supplement. People with severe or treatment-resistant depression, or whose bouts of depression […]

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