Phage therapy draws renewed interest to combat drug-resistant microbes

The married professors were spending their Thanksgiving holiday in Egypt when the husband, Thomas L. Patterson, Ph.D., got very sick very quickly, experiencing fever, nausea and a racing heartbeat. By the time Patterson was accurately diagnosed with a highly multi-drug resistant bacterial infection, he was near death. His wife, Steffanie Strathdee, Ph.D., promised to “leave no stone unturned.’” What happened […]

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New clues about how our body guards against cancer

Walter and Eliza Hall Institute researchers have uncovered a key factor protecting against age-related DNA damage, providing important clues about how our body guards against cancer. The discovery was made by identifying a rare genetic mutation in three patients with an unusual, early-onset form of acute myeloid leukaemia (AML). The patients all lacked a DNA repair protein called MBD4, which […]

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Duvelisib has marked response, survival benefit in difficult-to-treat leukemia and lymphoma

For some patients with difficult-to-treat leukemia and lymphoma, the investigational oral medicine duvelisib may significantly improve disease outcomes, according to phase III trial data published today in the journal Blood. The DUO trial studied the head-to-head comparison of duvelisib versus ofatumumab, an approved standard-of-care chemotherapy for relapsed or treatment-resistant chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). According to […]

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US, Japanese pair win Nobel Medicine Prize for cancer therapy

Two immunologists, James Allison of the US and Tasuku Honjo of Japan, won the 2018 Nobel Medicine Prize for research that has revolutionised the treatment of cancer, the jury said on Monday. The pair were honoured “for their discovery of cancer therapy by inhibition of negative immune regulation,” the Nobel Assembly said. Immune checkpoint inhibitor therapy targets proteins made by […]

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Too Faced Just Launched a Pumpkin Spice Makeup Collection — But There's a Catch

In September 2017, Instagram user @xstardustgirlx conjured up her own vision of what a pumpkin spice eyeshadow palette might look like. They attributed the hypothetical to none other than Too Faced — a logical choice considering the makeup brand had already launched a host of other food-themed products, from the Sweet Peach collection to the Chocolate Bar palettes. The post […]

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