Lesbian, bi women more likely to develop T2DM at younger age
(HealthDay)—Lesbian and bisexual (LB) women are more likely to develop type 2 diabetes at a younger age than heterosexual women, with the difference mediated by body mass index (BMI), according to a study published online May 2 in Diabetes Care.
Heather L. Corliss, M.P.H., Ph.D., from San Diego State University, and colleagues prospectively followed women participating in the Nurses’ Health Study II ages 24 to 44 years in 1989 through 2013. Of the participants, 1,267 identified as lesbian or bisexual and 92,938 were heterosexual. The incidence of type 2 diabetes was assessed based on self-reported clinician diagnosis.
The researchers found that the risk of developing type 2 diabetes was increased for LB women versus heterosexual women (adjusted incidence rate ratio, 1.27; 95 percent confidence interval, 1.05 to 1.54). The differences in the risk of type 2 diabetes were greater during younger ages (sexual orientation-by-age interaction, P < 0.001). The correlation between sexual orientation and type 2 diabetes was mediated by BMI; the incidence rate ratio was attenuated when BMI was added to the model (adjusted incidence rate ratio, 0.85; 95 percent confidence interval, 0.70 to 1.03).
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